Recombinant Human GAS-7 protein is a Human Fragment protein, in the 1 to 416 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- Tag free
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M K P G M V P P P P G E E S Q T V I L P P G W Q S Y L S P Q G R R Y Y V N T T T N E T T W E R P S S S P G I P A S P G S H R S S L P P T V N G Y H A S G T P A H P P E T A H M S V R K S T G D S Q N L G S S S P S K K Q S K E N T I T I N C V T F P H P D T M P E Q Q L L K P T E W S Y C D Y F W A D K K D P Q G N G T V A G F E L L L Q K Q L K G K Q M Q K E M S E F I R E R I K I E E D Y A K N L A K L S Q N S L A S Q E E G S L G E A W A Q V K K S L A D E A E V H L K F S A K L H S E V E K P L M N F R E N F K K D M K K C D H H I A D L R K Q L A S R Y A S V E K A R K A L T E R Q R D L E M K T Q Q L E I K L S N K T E E D I K K A R R K S T Q A G D D L M R C V D L Y N Q A Q S K W F E E M V T T T L E L E R L E V E R V E M I R Q H L C Q Y T Q L R H E T D M F N Q S T V E P V D Q L L R K V D P A K D R E L W V R E H K T G N I R P V D M E I
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
Alternative names
KIAA0394, GAS7, Growth arrest-specific protein 7, GAS-7
Recommended products
Recombinant Human GAS-7 protein is a Human Fragment protein, in the 1 to 416 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- Tag free
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- O60861-3
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0308% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M K P G M V P P P P G E E S Q T V I L P P G W Q S Y L S P Q G R R Y Y V N T T T N E T T W E R P S S S P G I P A S P G S H R S S L P P T V N G Y H A S G T P A H P P E T A H M S V R K S T G D S Q N L G S S S P S K K Q S K E N T I T I N C V T F P H P D T M P E Q Q L L K P T E W S Y C D Y F W A D K K D P Q G N G T V A G F E L L L Q K Q L K G K Q M Q K E M S E F I R E R I K I E E D Y A K N L A K L S Q N S L A S Q E E G S L G E A W A Q V K K S L A D E A E V H L K F S A K L H S E V E K P L M N F R E N F K K D M K K C D H H I A D L R K Q L A S R Y A S V E K A R K A L T E R Q R D L E M K T Q Q L E I K L S N K T E E D I K K A R R K S T Q A G D D L M R C V D L Y N Q A Q S K W F E E M V T T T L E L E R L E V E R V E M I R Q H L C Q Y T Q L R H E T D M F N Q S T V E P V D Q L L R K V D P A K D R E L W V R E H K T G N I R P V D M E I
- Accession
- O60861
- Protein length
- Fragment
- Amino acids
- 1 to 416
- Nature
- Recombinant
Specifications
- Form
- Liquid
- Additional notes
ab84332 is purified using conventional chromatography techniques.Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method).
General info
- Function
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Previously labelled as Growth Arrest Specific Protein 7.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Growth Arrest-Specific 7 often known as GAS7 is a protein with a molecular weight of approximately 48 kDa. GAS7 is known for its expression in neural tissues particularly in the brain where it plays an important role in cellular processes. This protein participates in the growth arrest of cells specifically in neurons indicating its importance in neurological functions.
- Biological function summary
GAS7 contributes to the regulation of neuronal development and morphology. It is a part of various cellular complexes that guide the proper formation and differentiation of neurons. Studies show it helps in the development of the nerve cell cytoskeleton which is critical for maintaining neuronal architecture and function.
- Pathways
The involvement of GAS7 includes those related to cytoskeletal organization and neuronal differentiation. Two significant pathways include the MAPK signaling pathway and the PI3K-Akt signaling pathway. GAS7 interacts with other proteins such as actin and filamin which are essential components in these pathways to regulate cell shape and motility.
- Associated diseases and disorders
GAS7 is linked to certain neurological conditions like neurodegenerative disorders and developmental issues. Abnormalities in GAS7 expression or function may have connections to disorders like Alzheimer's disease where cytoskeletal anomalies are common. Additionally its interaction with the protein tau which is implicated in Alzheimer's highlights its potential role in the manifestation of such diseases.
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1 product image
SDS-PAGE - Recombinant Human GAS-7 protein (ab84332)
15% SDS-PAGE showing ab84332 (3μg).
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