JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB164034

Recombinant Human GCC1 protein

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human GCC1 protein is a Human Full Length protein, in the 1 to 775 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

GRIP and coiled-coil domain-containing protein 1, Golgi coiled-coil protein 1, GCC1

1 Images
SDS-PAGE - Recombinant Human GCC1 protein (AB164034)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human GCC1 protein (AB164034)

ab164034 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Q96CN9

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLAGVQLPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFGVEDDRPARGPPPPKSEEASWSESGVSSSSGDGPFAGGEVDKRLHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEEELHKQRDRALAVLTEKDLELEQLRSVALASGLPGRRSPVGGGGPGDPADTSSSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEVHQLQDRLLEEGERHREEVAALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVIMRLPTSASWWPSGKR","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":775,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q96CN9","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

GCC1 also known as Golgi coiled-coil protein 1 is a protein with a mass of approximately 82 kDa. It mainly localizes to the Golgi apparatus and plays a significant role in the Golgi structure and function. GCC1 engages with various proteins to support Golgi cisternal stacking and maintenance of Golgi morphology. It is expressed in multiple tissues with higher expression levels detected in organs with secretory functions.
Biological function summary

GCC1 interacts within protein complexes that govern the trafficking and sorting of proteins through the Golgi apparatus. It contributes to the regulation of retrograde transport moving proteins from the Golgi back to the endoplasmic reticulum. GCC1 partners with Rab GTPases which are vital for vesicle formation and cargo recognition therefore facilitating efficient intracellular transport and processing.

Pathways

GCC1 participates in critical cellular processes including the Golgi-to-ER retrograde transport and the broader protein secretion pathway. It works closely with proteins such as Rab6 which is necessary for the regulation of this pathway. Through these interactions GCC1 ensures optimal function and communication between cellular compartments involved in the secretory process.

GCC1 has associations with conditions such as neurodegenerative diseases and cancer. Aberrant expression or mutation of GCC1 may contribute to Golgi fragmentation which has been observed in various neurological disorders. Additionally GCC1 interactions with proteins like SNAREs may have implications in tumorigenesis as defects in vesicular transport can influence cancer progression.
style
left-column

Specifications

Form

Liquid

style
left-column

General info

Function

Probably involved in maintaining Golgi structure.

style
left-column

Product protocols

style
left-column

Target data

Probably involved in maintaining Golgi structure.
See full target information GCC1
style
left-column
style
left-column
style
right-column

Complementary Products

Proteins & Peptides

AB164178

Recombinant Human Dock5 protein

SDS-PAGE - Recombinant Human Dock5 protein (AB164178)

  • 0
  • 0
Proteins & Peptides

AB163782

Recombinant Human VISTA protein

SDS-PAGE - Recombinant Human VISTA protein (AB163782)

  • 0
  • 0
Proteins & Peptides

AB164054

Recombinant Human TIPE2 protein

SDS-PAGE - Recombinant Human TIPE2 protein (AB164054)

  • 0
  • 0
Proteins & Peptides

AB163740

Recombinant Human TRAPPC11 protein

SDS-PAGE - Recombinant Human TRAPPC11 protein (AB163740)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com