Recombinant Human GDF8 / Myostatin protein (His tag)
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Recombinant Human GDF8 / Myostatin protein (His tag) is a Human Full Length protein, in the 267 to 375 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
GDF8, MSTN, Growth/differentiation factor 8, GDF-8, Myostatin
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human GDF8 / Myostatin protein (His tag) (AB238360)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab238360.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
Specifications
Form
Liquid
General info
Function
Acts specifically as a negative regulator of skeletal muscle growth.
Sequence similarities
Belongs to the TGF-beta family.
Post-translational modifications
Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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