Recombinant Human GFR alpha 3/GFRA3 protein (denatured) is a Human Full Length protein, in the 32 to 374 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S D P L P T E S R L M N S C L Q A R R K C Q A D P T C S A A Y H H L D S C T S S I S T P L P S E E P S V P A D C L E A A Q Q L R N S S L I G C M C H R R M K N Q V A C L D I Y W T V H R A R S L G N Y E L D V S P Y E D T V T S K P W K M N L S K L N M L K P D S D L C L K F A M L C T L N D K C D R L R K A Y G E A C S G P H C Q R H V C L R Q L L T F F E K A A E P H A Q G L L L C P C A P N D R G C G E R R R N T I A P N C A L P P V A P N C L E L R R L C F S D P L C R S R L V D F Q T H C H P M D I L G T C A T E Q S R C L R A Y L G L I G T A M T P N F V S N V N T S V A L S C T C R G S G N L Q E E C E M L E G F F S H N P C L T E A I A A K M R F H S Q L F S Q D W P H P T F A V M A H Q N E N
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
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Target data
Function
Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons (PubMed:31535977, PubMed:9883723). ARTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977, PubMed:9883723).
Alternative names
UNQ339/PRO538/PRO3664, GFRA3, GDNF family receptor alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GFR-alpha-3
Recommended products
Recombinant Human GFR alpha 3/GFRA3 protein (denatured) is a Human Full Length protein, in the 32 to 374 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- O60609-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M G S D P L P T E S R L M N S C L Q A R R K C Q A D P T C S A A Y H H L D S C T S S I S T P L P S E E P S V P A D C L E A A Q Q L R N S S L I G C M C H R R M K N Q V A C L D I Y W T V H R A R S L G N Y E L D V S P Y E D T V T S K P W K M N L S K L N M L K P D S D L C L K F A M L C T L N D K C D R L R K A Y G E A C S G P H C Q R H V C L R Q L L T F F E K A A E P H A Q G L L L C P C A P N D R G C G E R R R N T I A P N C A L P P V A P N C L E L R R L C F S D P L C R S R L V D F Q T H C H P M D I L G T C A T E Q S R C L R A Y L G L I G T A M T P N F V S N V N T S V A L S C T C R G S G N L Q E E C E M L E G F F S H N P C L T E A I A A K M R F H S Q L F S Q D W P H P T F A V M A H Q N E N
- Accession
- O60609
- Protein length
- Full Length
- Predicted molecular weight
- 40.7 kDa
- Amino acids
- 32 to 374
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons (PubMed:31535977, PubMed:9883723). ARTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977, PubMed:9883723).
- Sequence similarities
Belongs to the GDNFR family.
- Post-translational modifications
N-glycosylated.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
This product was previously labelled as GFR alpha 3
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1 product image
SDS-PAGE - Recombinant Human GFR alpha 3/GFRA3 protein (denatured) (ab174556)
15% SDS-PAGE analysis of ab174556 (3μg).
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