Recombinant Human GIMAP6 protein (His tag N-Terminus)
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Recombinant Human GIMAP6 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 292 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
IAN2, IAN6, GIMAP6, GTPase IMAP family member 6, Immunity-associated nucleotide 2 protein, Immunity-associated nucleotide 6 protein, IAN-2, hIAN2, IAN-6, hIAN6
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human GIMAP6 protein (His tag N-Terminus) (AB167915)
15% SDS-PAGE analysis of 3 μg ab167915
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The functions involving GTPase such as GIMAP6 regulate immune cell survival and homeostasis. It participates in critical cellular processes like apoptosis and autophagy often interacting with other members of the GIMAP family. GIMAP6 involvement suggests its integration in protein complexes that maintain cellular balance and response to stressors. Due to these activities GIMAP6 helps to modulate cell fate decisions in lymphocytes and perhaps other immune cells.
Pathways
Knowledge about GIMAP6 connects it to the regulation of autophagy and apoptosis pathways. It possibly interacts with molecules like Beclin-1 which plays a central role in the autophagy pathway. These interactions imply a connection to the PI3K/Akt signaling pathway where GIMAP proteins can influence survival signals and cellular responses. Therefore GIMAP6 has the potential to intersect with pathways involving other GTPase family proteins highlighting its influence within immune signaling networks.
Specifications
Form
Liquid
Additional notes
purified by using conventional chromatography techniques.
General info
Sequence similarities
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Target data
Product promise
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