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AB276331

Recombinant Human GLIPR1 protein (His tag)

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Recombinant Human GLIPR1 protein (His tag) is a Human Fragment protein, in the 1 to 232 aa range, expressed in HEK 293 cells, with >97%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

GLIPR, RTVP1, GLIPR1, Glioma pathogenesis-related protein 1, GliPR 1, Protein RTVP-1

1 Images
SDS-PAGE - Recombinant Human GLIPR1 protein (His tag) (AB276331)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human GLIPR1 protein (His tag) (AB276331)

SDS-PAGE analysis of ab276331

Key facts

Purity

>97% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P48060

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

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Complementary Products

Primary Antibodies

AB133357

Anti-CD11b antibody [EPR1344]

BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant|Lab Essentials|20ul selling size

Multiplex immunohistochemistry - Anti-CD11b antibody [EPR1344] (AB133357)

  • 4
  • 37
Primary Antibodies

AB11029

Anti-CD11c antibody [3.9]

Trial Size

Flow Cytometry - Anti-CD11c antibody [3.9] (AB11029)

  • 4
  • 11
Primary Antibodies

AB198215

Anti-GLIPR1 antibody

Western blot - Anti-GLIPR1 antibody (AB198215)

  • 0
  • 0
Primary Antibodies

AB233005

Anti-PLSCR4 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLSCR4 antibody (AB233005)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MRVTLATIAWMVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDEIQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGNYPTWPYKRGATCSACPNNDKCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNR","proteinLength":"Fragment","predictedMolecularWeight":"25.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":232,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P48060","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

GLIPR1 also known as Glioma Pathogenesis Related Protein 1 functions mechanically as a protein involved in cellular processes. Its mass is approximately 39 kDa. Researchers have found it expressed in various tissues such as the kidney lung prostate and brain. The protein occurs at higher levels in certain tumor cells suggesting a significant role in cancer biology. Different studies also refer to this protein as GLIPR1L1 or CRISP4 highlighting its complexity.
Biological function summary

GLIPR1 plays an important role in regulating the immune response and apoptosis affecting cellular survival and death. It can influence cell adhesion and motility essential for normal tissue maintenance and response to injury. GLIPR1 acts as part of larger cellular complexes that modulate critical cellular functions. It shows interaction with the tumor suppressor p53 further emphasizing its role in tumorigenesis and cell cycle regulation.

Pathways

GLIPR1 integrates into the p53 signaling and apoptosis pathways affecting how cells respond to stress and damage. The protein interacts with several components including p53 itself to mediate cellular apoptosis. GLIPR1 also participates in mechanisms that regulate inflammation possibly linking it to immune system pathways alongside proteins like NF-kB which plays a role in inflammatory responses.

Researchers have associated GLIPR1 with cancers notably prostate and glioblastoma. The protein's abnormal expression correlates with tumor progression and patient prognosis. GLIPR1 also connects to inflammatory disorders due to its role in modulating immune responses. Its interaction with p53 highlights its significance in cancer pathogenesis making it a target for potential therapeutic strategies.
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Specifications

Form

Lyophilized

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General info

Sequence similarities

Belongs to the CRISP family.

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Product protocols

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Target data

See full target information GLIPR1
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Product promise

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