Recombinant Human Glycogenin 1 protein
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Recombinant Human Glycogenin 1 protein is a Human Full Length protein, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
GYG, GYG1, Glycogenin-1, GN-1, GN1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Glycogenin 1 protein (AB87624)
15% SDS-PAGE showing ab87624 at approximately 41.2 kDa (3μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Glycogenin 1 serves as the foundation for glycogen granule formation by providing the initial glucose chain that glycogen synthase can extend. The protein participates in the formation of a macromolecular complex that includes glycogen synthase and glycogen branching enzyme facilitating efficient glycogen deposition. The association with these enzymes ensures that the glycogen is structured properly optimizing cellular energy storage. Glycogenin 1 acts as the core around which all further glucose additions are built making it indispensable for maintaining energy reserves.
Pathways
Glycogenin 1 is integral to glycogen metabolism. It plays a critical role within the glycogen biosynthesis pathway closely interacting with proteins such as glycogen synthase and the branching enzyme. The coordinated activity of Glycogenin 1 glycogen synthase and the branching enzyme is necessary for the proper assembly of glycogen particles. This pathway regulation impacts glucose homeostasis and energy management in muscle and liver tissues indicating its importance for metabolic balance.
Specifications
Form
Liquid
Additional notes
ab87624 is purified using conventional chromatography techniques.
General info
Function
Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.
Sequence similarities
Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.
Post-translational modifications
Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195.. Phosphorylated.
Target data
Complementary Products
Product promise
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