JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB314629

Recombinant Human GPR157 Protein (His Tag)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human GPR157 Protein (His Tag) is a Human Full Length protein, in the 1 to 335 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
1 Images
SDS-PAGE - Recombinant Human GPR157 Protein (His Tag) (AB314629)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human GPR157 Protein (His Tag) (AB314629)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

10x His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q5UAW9-1

Animal free

Yes

Carrier free

No

Species

Human

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Storage buffer

pH: 7.4 - 8 Constituents: PBS, 6% Trehalose

storage-buffer

style
left-column

Complementary Products

Proteins & Peptides

AB160463

Recombinant Human Neurexin 1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Neurexin 1 protein (GST tag N-Terminus) (AB160463)

  • 0
  • 0
Proteins & Peptides

AB151351

Recombinant Human Angiogenin protein

  • 0
  • 0
Assay Kits

AB110217

MitoBiogenesis™ In-Cell ELISA Kit (Colorimetric)

In-Cell ELISA - MitoBiogenesis™ In-Cell ELISA Kit (Colorimetric) (AB110217)

  • 5
  • 2
Primary Antibodies

AB33279

FITC Anti-P-Selectin (CD62P) antibody [AK-6]

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"linker":null,"sequence":"MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQNFAGPSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRAARGPRTDRLLWAFHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWIDLEAKDHVLWMLLTGKLWEMLAYVLLPLLYLLVRKHINRAHTALSEYRPILSQEHRLLRHSSMADKKLVLIPLIFIGLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCCSSQPPTKSPAGTPKAPAPSKPGESQESQGTPGELPST","proteinLength":"Full Length","predictedMolecularWeight":"39.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":335,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q5UAW9","tags":[{"tag":"10x His","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Form
Lyophilized
Purification technique
Ion exchange chromatography
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Add glycerol to a final volume of 50% for extra stability and aliquot
Storage information
The product can be stored for up to 12 months
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

G protein-coupled receptor 157 also known as GPR157 is a member of the GPCR family involved in cell signaling. This protein has a significant role in signal transmission across cell membranes. The molecular mass of GPR157 is approximately 38 kDa. GPR157 is expressed in a variety of tissues with notable expression within the brain indicating its involvement in neurological processes.
Biological function summary

GPR157 influences various processes by modulating intracellular signaling pathways. It participates in forming complexes with other cellular proteins contributing to significant biological activities. The protein is known for its role in neural development and function. It interacts with other receptors and signaling molecules within the cell to regulate brain-related mechanisms showing its importance in neurobiology.

Pathways

GPR157 plays a critical role in the Wnt signaling pathway and the neurotrophic factor-mediated pathway. Through these pathways GPR157 interacts with other proteins like β-catenin and TrkB which are important for signal transduction related to cell growth and survival. This involvement highlights its significance in maintaining normal cellular processes and preventing abnormal signaling.

GPR157 has implications in neurological conditions and psychiatric disorders notably schizophrenia and neurodegenerative diseases. There are associations between GPR157 and dysregulated signaling processes involving proteins like dopamine receptors which could lead to improper brain functioning. Studying GPR157 provides insights into potential therapeutic targets for these conditions.
style
left-column

Product protocols

style
left-column

Target data

Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
See full target information human G-protein coupled receptor 157

Alternative Names

G-protein coupled receptor 157, GPR157
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com