Recombinant Human GSTA1 protein
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Recombinant Human GSTA1 protein is a Human Full Length protein, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, WB.
View Alternative Names
Glutathione S-transferase A1, 13-hydroperoxyoctadecadienoate peroxidase, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, GSTA1
- WB
Unknown
Western blot - Recombinant Human GSTA1 protein (AB95381)
All lanes:
Anti-GSTA1 antibody (<a href='/en-us/products/unavailable/gsta1-antibody-ab96043'>ab96043</a>) at 1 µg/mL
Lane 1:
Western blot - Recombinant Human GSTA1 protein (ab95381) at 0.1 µg
Lane 2:
Western blot - Recombinant Human GSTA1 protein (ab95381) at 0.01 µg
Secondary
All lanes:
Western blot - Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-preadsorbed-ab97080'>ab97080</a>) at 1/5000 dilution
true
Exposure time: 8min
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human GSTA1 protein (AB95381)
15% SDS-PAGE image (3ug) generated using ab95381
Reactivity data
Product details
Previously labelled as Glutathione S Transferase alpha 1.
Previously labelled as Glutathione S Transferase alpha 1.
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The GSTA1 protein contributes significantly to the neutralization of oxidative stress by detoxifying harmful compounds. This enzyme shows a high affinity for certain substrates and serves as a detoxifying agent particularly in the liver safeguarding cells from oxidative damage. GSTA1 exists mostly as a homodimer but can also form heterodimers with other related enzymes enhancing its substrate range and activity.
Pathways
GSTA1 plays a role in metabolic and detoxification pathways essential for cellular protection. It is an important player in the glutathione metabolism pathway where it collaborates with other enzymes like GSTM1 to facilitate detoxification processes. Additionally GSTA1 participates in the pathways leading to the synthesis of mercapturic acids which are important for the excretion of toxic metabolites.
Specifications
Form
Liquid
Additional notes
purified by using conventional chromatography techniques
General info
Function
Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed : 9084911). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis (PubMed : 11152686). Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid (PubMed : 16624487).
Sequence similarities
Belongs to the GST superfamily. Alpha family.
Target data
Complementary Products
![Immunoprecipitation - Anti-GSTA1 antibody [EPR19969] (AB207413)](https://content.abcam.com/products/images/gsta1-antibody-epr19969-ab207413--immunoprecipitation-img12227.jpg)
Product promise
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