Recombinant Human GSTK1 protein (Tag Free)
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(1 Publication)
Recombinant Human GSTK1 protein (Tag Free) is a Human Full Length protein, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
HDCMD47P, GSTK1, Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, Glutathione S-transferase subunit 13, hGSTK1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human GSTK1 protein (Tag Free) (AB93457)
15% SDS-PAGE showing ab93457 at approximately 26 kDa (3 μg).
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
GSTK1 is part of the cellular defense mechanism against xenobiotic and oxidative stress. This enzyme participates in the neutralization of harmful compounds by facilitating their conjugation with glutathione a powerful antioxidant. GSTK1 functions independently and does not form part of a larger protein complex. Its activity is important in maintaining cellular homeostasis and preventing damage caused by reactive oxygen species.
Pathways
GSTK1 has critical involvement in glutathione metabolism and xenobiotic detoxification pathways. It interacts functionally with proteins like GSTM1 which are also part of the glutathione S-transferase family enhancing the cell’s ability to detoxify harmful substances. GSTK1 helps to modulate the cellular response to oxidative stress through these pathways ensuring protection against toxicity.
Specifications
Form
Liquid
Additional notes
ab93457 is purified using conventional chromatography techniques.
General info
Function
Glutathione S-transferase that catalyzes the conjugation of glutathione to exogenous and endogenous compounds (PubMed : 14709161, PubMed : 14742434). Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB) (PubMed : 14709161).
Sequence similarities
Belongs to the GST superfamily. Kappa family.
Subcellular localisation
Peroxisome
Target data
Publications (1)
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Cell chemical biology 26:449-461.e8 PubMed30713096
2019
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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