Recombinant Human GSTT2 protein (His tag)
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Recombinant Human GSTT2 protein (His tag) is a Human Full Length protein, in the 1 to 244 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
View Alternative Names
GSTT2, GSTT2B, Glutathione S-transferase theta-2B, Glutathione S-transferase theta-2, GST class-theta-2
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human GSTT2 protein (His tag) (AB276665)
SDS-PAGE analysis of ab276665.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
GSTT2 facilitates the detoxification process by catalyzing reactions that neutralize harmful compounds. It catalyzes the conjugation of glutathione to form less reactive electrophilic or hydrophobic substances. GSTT2 does not function as part of a larger complex within cells but has an important role in maintaining the redox balance. The enzyme contributes to cellular defense mechanisms ensuring proper cellular functions in stressful environments.
Pathways
The activity of GSTT2 has connections to the glutathione metabolism and drug metabolism pathways. These pathways are important for neutralizing endogenous and exogenous toxins. In the glutathione metabolism pathway GSTT2 works in conjunction with other GST enzymes like GSTP1 and GSTA1 to manage oxidative stress. The protein indirectly supports cellular detoxification processes influencing how effectively a cell can endure and adapt to toxic insults.
Specifications
Form
Lyophilized
General info
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed : 1417752). Has a sulfatase activity (PubMed : 1417752).
Sequence similarities
Belongs to the GST superfamily. Theta family.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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