Recombinant Human GTF3C6 protein (His tag N-Terminus)
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Recombinant Human GTF3C6 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 213 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
C6orf51, CDA020, NPD020, GTF3C6, General transcription factor 3C polypeptide 6, Transcription factor IIIC 35 kDa subunit, Transcription factor IIIC subunit 6, TFIIIC 35 kDa subunit, TFIIIC35
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human GTF3C6 protein (His tag N-Terminus) (AB187441)
15% SDS-PAGE analysis of 3 μg of ab187441.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The protein contributes to the transcription of small non-coding RNA genes such as 5S rRNA and tRNAs. GTF3C6 is a subunit of the TFIIIC complex and its function involves the recognition of specific promoter elements on DNA which is imperative for initiating transcription. By participating in the recognition and structuring of promoter regions GTF3C6 ensures proper transcription activation necessary for cell growth and metabolism.
Pathways
The engagement of GTF3C6 in RNA polymerase III transcription is significant. It operates within the RNA polymerase III transcription pathways interacting with TFIIIB and RNA polymerase III which are key components of the transcription machinery. GTF3C6 plays a role in the complex network of transcription regulation ensuring the timely transcription of essential RNAs that regulate protein synthesis and cell cycle progression.
Specifications
Form
Liquid
Additional notes
ab187441 was purified using conventional chromatography techniques.
General info
Function
Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.
Sequence similarities
Belongs to the TFIIIC subunit 6 family.
Subcellular localisation
Nucleus
Target data
Complementary Products
Product promise
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