Recombinant Human HDHD1A protein
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Recombinant Human HDHD1A protein is a Human Full Length protein, in the 1 to 228 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A, PUDP, Pseudouridine-5'-phosphatase, Haloacid dehalogenase-like hydrolase domain-containing protein 1, Haloacid dehalogenase-like hydrolase domain-containing protein 1A, Protein GS1, Pseudouridine-5'-monophosphatase, 5'-PsiMPase
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human HDHD1A protein (AB101212)
15% SDS-PAGE analysis of 3μg ab101212.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
HDHD1A plays an essential role in regulating serine phosphorylation status within cells affecting multiple signaling pathways and cellular functions. Although HDHD1A does not form part of larger protein complexes its activity influences the phosphorylation landscape facilitating protein-protein interactions and modulating downstream effects. This regulatory ability helps maintain phosphorylation equilibrium arguably impacting cell growth and division processes.
Pathways
HDHD1A becomes involved in cellular signal transduction and metabolic pathways by modulating protein phosphorylation states. One significant pathway includes the MAPK (mitogen-activated protein kinase) signaling cascade which profoundly influences cell proliferation differentiation and apoptosis. Within these pathways proteins like ERK (extracellular signal-regulated kinase) and MEK (MAPK/ERK kinase) could relate closely to HDHD1A's activity affecting overall pathway dynamics and cellular responses.
Specifications
Form
Liquid
Additional notes
ab101212 was purified using conventional chromatography.
General info
Function
Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.
Sequence similarities
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Target data
Complementary Products
Product promise
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