Recombinant Human HDHD2 protein is a Human Full Length protein, in the 1 to 259 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
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Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M A A C R A L K A V L V D L S G T L H I E D A A V P G A Q E A L K R L R G A S V I I R F V T N T T K E S K Q D L L E R L R K L E F D I S E D E I F T S L T A A R S L L E R K Q V R P M L L V D D R A L P D F K G I Q T S D P N A V V M G L A P E H F H Y Q I L N Q A F R L L L D G A P L I A I H K A R Y Y K R K D G L A L G P G P F V T A L E Y A T D T K A T V V G K P E K T F F L E A L R G T G C E P E E A V M I G D D C R D D V G G A Q D V G M L G I L V K T G K Y R A S D E E K I N P P P Y L T C E S F P H A V D H I L Q H L L
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Target data
Alternative names
Haloacid dehalogenase-like hydrolase domain-containing protein 2, HDHD2
Recommended products
Recombinant Human HDHD2 protein is a Human Full Length protein, in the 1 to 259 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- Q9H0R4-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M A A C R A L K A V L V D L S G T L H I E D A A V P G A Q E A L K R L R G A S V I I R F V T N T T K E S K Q D L L E R L R K L E F D I S E D E I F T S L T A A R S L L E R K Q V R P M L L V D D R A L P D F K G I Q T S D P N A V V M G L A P E H F H Y Q I L N Q A F R L L L D G A P L I A I H K A R Y Y K R K D G L A L G P G P F V T A L E Y A T D T K A T V V G K P E K T F F L E A L R G T G C E P E E A V M I G D D C R D D V G G A Q D V G M L G I L V K T G K Y R A S D E E K I N P P P Y L T C E S F P H A V D H I L Q H L L
- Accession
- Q9H0R4
- Protein length
- Full Length
- Predicted molecular weight
- 30.6 kDa
- Amino acids
- 1 to 259
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab101940 is purified using conventional chromatography techniques.
General info
- Sequence similarities
Belongs to the HAD-like hydrolase superfamily.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
HDHD2 also known as haloacid dehalogenase-like hydrolase domain-containing protein 2 is an enzyme with a molecular weight of approximately 22 kDa. It primarily functions as a phosphatase which removes phosphate groups from specific substrates. HDHD2 is expressed in several tissues including the liver and brain. Its activity is integral to regulating phosphate metabolism and maintaining cellular homeostasis.
- Biological function summary
HDHD2 hydrolyzes phosphoserines and plays an essential role in dephosphorylation processes. It is a component of protein complexes that control phosphorylation states within cells directly affecting protein functions. Through these actions HDHD2 influences cellular signaling and metabolism contributing to physiological processes such as enzyme regulation and substrate modification.
- Pathways
HDHD2 participates in signaling pathways related to phosphate metabolism and energy balance. It is related to the energy production pathway and the regulation of cellular signaling cascades. This protein interacts with other enzymes like PPARG and PTPMT1 coordinating the maintenance of phosphate balance across cellular compartments.
- Associated diseases and disorders
Abnormalities in HDHD2 function can be linked to metabolic disorders including diabetes and obesity. Its disturbance affects phosphate homeostasis and potentially contributes to insulin resistance. HDHD2 interacts with proteins such as insulin receptors and SREBP-1c implicating it in metabolic dysregulation associated with these conditions.
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1 product image
SDS-PAGE - Recombinant Human HDHD2 protein (ab101940)
15% SDS-PAGE analysis of 3μg ab101940.
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