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Recombinant Human Hex protein is a Human Full Length protein, in the 1 to 270 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.

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Key facts

Purity
>85% SDS-PAGE
Expression system
Escherichia coli
Tags
His tag N-Terminus
Applications
SDS-PAGE, MS
Biologically active
No

Amino acid sequence

M G S S H H H H H H S S G L V P R G S H M G S M Q Y P H P G P A A G A V G V P L Y A P T P L L Q P A H P T P F Y I E D I L G R G P A A P T P A P T L P S P N S S F T S L V S P Y R T P V Y E P T P I H P A F S H H S A A A L A A A Y G P G G F G G P L Y P F P R T V N D Y T H A L L R H D P L G K P L L W S P F L Q R P L H K R K G G Q V R F S N D Q T I E L E K K F E T Q K Y L S P P E R K R L A K M L Q L S E R Q V K T W F Q N R R A K W R R L K Q E N P Q S N K K E E L E S L D S S C D Q R Q D L P S E Q N K G A S L D S S Q C S P S P A S Q E D L E S E I S E D S D Q E V D I E G D K S Y F N A G

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Application
MS
Reactivity
Reacts
Dilution info
-
Notes

-

Associated Products

Select an associated product type

1 product for Alternative Product

Target data

Function

Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). Inhibits EIF4E-mediated mRNA nuclear export (PubMed:12554669). May play a role in hematopoietic differentiation (PubMed:8096636).

Alternative names

Recommended products

Recombinant Human Hex protein is a Human Full Length protein, in the 1 to 270 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.

Key facts

Purity
>85% SDS-PAGE
Expression system
Escherichia coli
Applications
SDS-PAGE, MS
Accession
Q03014-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 8
Constituents: 40% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

Sequence info

Amino acid sequence

M G S S H H H H H H S S G L V P R G S H M G S M Q Y P H P G P A A G A V G V P L Y A P T P L L Q P A H P T P F Y I E D I L G R G P A A P T P A P T L P S P N S S F T S L V S P Y R T P V Y E P T P I H P A F S H H S A A A L A A A Y G P G G F G G P L Y P F P R T V N D Y T H A L L R H D P L G K P L L W S P F L Q R P L H K R K G G Q V R F S N D Q T I E L E K K F E T Q K Y L S P P E R K R L A K M L Q L S E R Q V K T W F Q N R R A K W R R L K Q E N P Q S N K K E E L E S L D S S C D Q R Q D L P S E Q N K G A S L D S S Q C S P S P A S Q E D L E S E I S E D S D Q E V D I E G D K S Y F N A G
Accession
Q03014
Protein length
Full Length
Predicted molecular weight
32 kDa
Amino acids
1 to 270
Nature
Recombinant
Tags
His tag N-Terminus

Specifications

Form
Liquid
Additional notes

ab167885 is purified using conventional chromatography techniques.

General info

Function

Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). Inhibits EIF4E-mediated mRNA nuclear export (PubMed:12554669). May play a role in hematopoietic differentiation (PubMed:8096636).

Subcellular localisation
Nucleus

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product promise

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