Recombinant Human HINT2 protein (His tag N-Terminus)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human HINT2 protein (His tag N-Terminus) is a Human Full Length protein, in the 18 to 163 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
Adenosine 5'-monophosphoramidase HINT2, HINT-3, HIT-17kDa, PKCI-1-related HIT protein, HINT-2, HINT2
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human HINT2 protein (His tag N-Terminus) (AB156323)
15% SDS-PAGE anaysis of ab156323 (3μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This protein influences several cellular processes including apoptosis and mitochondrial function regulation. HINT2 is not part of a larger protein complex but works independently to ensure proper mitochondrial activity. Through these actions HINT2 maintains cellular homeostasis which is important for healthy energy production and utilization within the cell.
Pathways
This protein interacts with key signaling pathways such as the mitochondrial apoptosis pathway. This pathway usually relates to programmed cell death and links closely with proteins like cytochrome c and caspases. By influencing this pathway HINT2 plays a part in determining cell fate and contributes to the balance between cell survival and death.
Specifications
Form
Liquid
Additional notes
ab156323 is purified using conventional chromatography techniques.
General info
Function
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed : 16762638, PubMed : 31990367). Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) (PubMed : 16762638). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed : 31990367). May be involved in steroid biosynthesis (PubMed : 18653718). May play a role in apoptosis (PubMed : 16762638).
Sequence similarities
Belongs to the HINT family.
Subcellular localisation
Mitochondrion
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com