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AB156333

Recombinant Human HMGA2 protein (His tag C-Terminus)

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Recombinant Human HMGA2 protein (His tag C-Terminus) is a Human Full Length protein, in the 1 to 109 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE.

View Alternative Names

HMGIC, HMGA2, High mobility group protein HMGI-C, High mobility group AT-hook protein 2

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SDS-PAGE - Recombinant Human HMGA2 protein (His tag C-Terminus) (AB156333)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human HMGA2 protein (His tag C-Terminus) (AB156333)

15% SDS-PAGE analysis of ab156333 (3μg).

Key facts

Purity

>80% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P52926

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Preservative: 1.7% Imidazole Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris HCl, 0.03% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEEDLEHHHHHH","proteinLength":"Full Length","predictedMolecularWeight":"12.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":109,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P52926","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab156333 is purified using conventional chromatography techniques.

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General info

Function

Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (PubMed : 28796236).

Sequence similarities

Belongs to the HMGA family.

Post-translational modifications

Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2 (By similarity).

Subcellular localisation

Nucleus

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Product protocols

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Target data

Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (PubMed : 28796236).
See full target information HMGA2
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Product promise

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