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Recombinant Human HNF-4-alpha protein is a Human Full Length protein, in the 1 to 464 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
Alternative names=Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4, TCF-14, HNF4A, TCF14, HNF4, NR2A1
Wheat germ
Tag free
SDS-PAGE, ELISA, WB
No
M R L S K T L V D M D M A D Y S A A L D P A Y T T L E F E N V Q V L T M G N D T S P S E G T N L N A P N S L G V S A L C A I C G D R A T G K H Y G A S S C D G C K G F F R R S V R K N H M Y S C R F S R Q C V V D K D K R N Q C R Y C R L K K C F R A G M K K E A V Q N E R D R I S T R R S S Y E D S S L P S I N A L L Q A E V L S R Q I T S P V S G I N G D I R A K K I A S I A D V C E S M K E Q L L V L V E W A K Y I P A F C E L P L D D Q V A L L R A H A G E H L L L G A T K R S M V F K D V L L L G N D Y I V P R H C P E L A E M S R V S I R I L D E L V L P F Q E L Q I D D N E Y A Y L K A I I F F D P D A K G L S D P G K I K R L R S Q V Q V S L E D Y I N D R Q Y D S R G R F G E L L L L L P T L Q S I T W Q M I E Q I Q F I K L F G M A K I D N L L Q E M L L G G S P S D A P H A H H P L H P H L M Q E H M G T N V I V A N T M P T H L S N G Q M S T P E T P Q P S P P G G S G S E P Y K L L P G A V A T I V K P L S A I P Q P T I T K Q E V I
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes (Recombinant protein). |
Recombinant Human HNF-4-alpha protein is a Human Full Length protein, in the 1 to 464 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
Alternative names=Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4, TCF-14, HNF4A, TCF14, HNF4, NR2A1
Wheat germ
Tag free
SDS-PAGE, ELISA, WB
No
78 kDa
1 to 464
M R L S K T L V D M D M A D Y S A A L D P A Y T T L E F E N V Q V L T M G N D T S P S E G T N L N A P N S L G V S A L C A I C G D R A T G K H Y G A S S C D G C K G F F R R S V R K N H M Y S C R F S R Q C V V D K D K R N Q C R Y C R L K K C F R A G M K K E A V Q N E R D R I S T R R S S Y E D S S L P S I N A L L Q A E V L S R Q I T S P V S G I N G D I R A K K I A S I A D V C E S M K E Q L L V L V E W A K Y I P A F C E L P L D D Q V A L L R A H A G E H L L L G A T K R S M V F K D V L L L G N D Y I V P R H C P E L A E M S R V S I R I L D E L V L P F Q E L Q I D D N E Y A Y L K A I I F F D P D A K G L S D P G K I K R L R S Q V Q V S L E D Y I N D R Q Y D S R G R F G E L L L L L P T L Q S I T W Q M I E Q I Q F I K L F G M A K I D N L L Q E M L L G G S P S D A P H A H H P L H P H L M Q E H M G T N V I V A N T M P T H L S N G Q M S T P E T P Q P S P P G G S G S E P Y K L L P G A V A T I V K P L S A I P Q P T I T K Q E V I
Full Length
No
Recombinant
Human
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Liquid
Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922). Activates the transcription of CYP2C38 (By similarity). Represses the CLOCK-ARNTL/BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells (PubMed:30530698).
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Phosphorylated on tyrosine residue(s); phosphorylation is important for its DNA-binding activity. Phosphorylation may directly or indirectly play a regulatory role in the subnuclear distribution. Phosphorylation at Ser-313 by AMPK reduces the ability to form homodimers and bind DNA.
Nucleus
Dry Ice
-80°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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