Recombinant Human HPS2 protein is a Human Fragment protein, in the 944 to 1094 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.
>95% SDS-PAGE
Escherichia coli
His-DHFR tag N-Terminus
SDS-PAGE
No
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
AP-3 complex subunit beta-1, Adaptor protein complex AP-3 subunit beta-1, Adaptor-related protein complex 3 subunit beta-1, Beta-3A-adaptin, Clathrin assembly protein complex 3 beta-1 large chain, ADTB3A, AP3B1
Recombinant Human HPS2 protein is a Human Fragment protein, in the 944 to 1094 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.
AP-3 complex subunit beta-1, Adaptor protein complex AP-3 subunit beta-1, Adaptor-related protein complex 3 subunit beta-1, Beta-3A-adaptin, Clathrin assembly protein complex 3 beta-1 large chain, ADTB3A, AP3B1
>95% SDS-PAGE
Escherichia coli
His-DHFR tag N-Terminus
SDS-PAGE
No
No
Human
Reconstitute with water to desired concentration.
Constituents: 0.58% Sodium chloride, 0.32% Tris HCl
Fragment
16.1 kDa
944 to 1094
Recombinant
His-DHFR tag N-Terminus
Lyophilized
Purified via His tag
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Belongs to the adaptor complexes large subunit family.
Phosphorylated on serine residues.
Blue Ice
-20°C
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