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AB127204

Recombinant Human HPSE2 protein

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(1 Publication)

Recombinant Human HPSE2 protein is a Human Fragment protein, in the 218 to 498 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE.

View Alternative Names

HPA2, HPSE2, Inactive heparanase-2, Hpa2

Key facts

Purity

>80% SDS-PAGE

Expression system

Escherichia coli

Tags

His-DHFR tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q8WWQ2

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in water

Storage buffer

Constituents: 0.58% Sodium chloride, 0.32% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":"33.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":498,"aminoAcidStart":218,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q8WWQ2","tags":[{"tag":"His-DHFR","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Lyophilized

Additional notes

Purified via His tag

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General info

Function

Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).

Sequence similarities

Belongs to the glycosyl hydrolase 79 family.

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Product protocols

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Target data

Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
See full target information HPSE2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of translational medicine 19:98 PubMed33663522

2021

Hypermethylation of heparanase 2 promotes colorectal cancer proliferation and is associated with poor prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Zhang,Chenxin Xu,Chen Shi,Junying Zhang,Ting Qian,Zhuo Wang,Rong Ma,Jianzhong Wu,Feng Jiang,Jifeng Feng
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