Recombinant Human IL-12RB1 protein (His tag) is a Human Fragment protein, in the 24 to 545 aa range, expressed in Insect, with >85% purity, < 1 EU/µg endotoxin level and suitable for MS, SDS-PAGE.
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Key facts
- Purity
- >85% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- Insect cells
- Tags
- His tag C-Terminus
- Applications
- MS, SDS-PAGE
- Biologically active
- No
Amino acid sequence
C R T S E C C F Q D P P Y P D A D S G S A S G P R D L R C Y R I S S D R Y E C S W Q Y E G P T A G V S H F L R C C L S S G R C C Y F A A G S A T R L Q F S D Q A G V S V L Y T V T L W V E S W A R N Q T E K S P E V T L Q L Y N S V K Y E P P L G D I K V S K L A G Q L R M E W E T P D N Q V G A E V Q F R H R T P S S P W K L G D C G P Q D D D T E S C L C P L E M N V A Q E F Q L R R R Q L G S Q G S S W S K W S S P V C V P P E N P P Q P Q V R F S V E Q L G Q D G R R R L T L K E Q P T Q L E L P E G C Q G L A P G T E V T Y R L Q L H M L S C P C K A K A T R T L H L G K M P Y L S G A A Y N V A V I S S N Q F G P G L N Q T W H I P A D T H T E P V A L N I S V G T N G T T M Y W P A R A Q S M T Y C I E W Q P V G Q D G G L A T C S L T A P Q D P D P A G M A T Y S W S R E S G A M G Q E K C Y Y I T I F A S A H P E K L T L W S T V L S T Y H F G G N A S A A G T P H H V S V K N H S L D S V S V D W A P S L L S T C P G V L K E Y V V R C R D E D S K Q V S E H P V Q P T E T Q V T L S G L R A G V A Y T V Q V R A D T A W L R G V W S Q P Q R F S I E V Q V S D H H H H H H
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes 50-70kDa (SDS-PAGE under reducing conditions) |
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Target data
Function
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Alternative names
CD212, IL12R, IL12RB, IL12RB1, Interleukin-12 receptor subunit beta-1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL-12 receptor beta component
Recommended products
Recombinant Human IL-12RB1 protein (His tag) is a Human Fragment protein, in the 24 to 545 aa range, expressed in Insect, with >85% purity, < 1 EU/µg endotoxin level and suitable for MS, SDS-PAGE.
Key facts
- Purity
- >85% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- Insect cells
- Tags
- His tag C-Terminus
- Applications
- MS, SDS-PAGE
- Biologically active
- No
- Accession
- P42701-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.03% EDTA, 0.002% PMSF
Sequence info
Amino acid sequence
- C R T S E C C F Q D P P Y P D A D S G S A S G P R D L R C Y R I S S D R Y E C S W Q Y E G P T A G V S H F L R C C L S S G R C C Y F A A G S A T R L Q F S D Q A G V S V L Y T V T L W V E S W A R N Q T E K S P E V T L Q L Y N S V K Y E P P L G D I K V S K L A G Q L R M E W E T P D N Q V G A E V Q F R H R T P S S P W K L G D C G P Q D D D T E S C L C P L E M N V A Q E F Q L R R R Q L G S Q G S S W S K W S S P V C V P P E N P P Q P Q V R F S V E Q L G Q D G R R R L T L K E Q P T Q L E L P E G C Q G L A P G T E V T Y R L Q L H M L S C P C K A K A T R T L H L G K M P Y L S G A A Y N V A V I S S N Q F G P G L N Q T W H I P A D T H T E P V A L N I S V G T N G T T M Y W P A R A Q S M T Y C I E W Q P V G Q D G G L A T C S L T A P Q D P D P A G M A T Y S W S R E S G A M G Q E K C Y Y I T I F A S A H P E K L T L W S T V L S T Y H F G G N A S A A G T P H H V S V K N H S L D S V S V D W A P S L L S T C P G V L K E Y V V R C R D E D S K Q V S E H P V Q P T E T Q V T L S G L R A G V A Y T V Q V R A D T A W L R G V W S Q P Q R F S I E V Q V S D H H H H H H
- Accession
- P42701
- Protein length
- Fragment
- Predicted molecular weight
- 58.4 kDa
- Amino acids
- 24 to 545
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Liquid
- Additional notes
Affinity purified
General info
- Function
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
- Sequence similarities
Belongs to the type I cytokine receptor family. Type 2 subfamily.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
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1 product image
SDS-PAGE - Recombinant Human IL-12RB1 protein (His tag) (ab201886)
15% SDS-PAGE analysis of ab201886 (3 μg).
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