Recombinant Human IL-13 receptor alpha 2 protein (denatured)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human IL-13 receptor alpha 2 protein (denatured) is a Human Fragment protein, in the 27 to 343 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
View Alternative Names
CD213a2, IL13R, IL13RA2, Interleukin-13 receptor subunit alpha-2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R-alpha-2, IL-13RA2, Interleukin-13-binding protein
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human IL-13 receptor alpha 2 protein (denatured) (AB156730)
15% SDS-PAGE analysis of 3µg ab156730.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Cell surface receptor that plays a role in the regulation of IL-13-mediated responses (PubMed : 11861389, PubMed : 17030238). Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation (PubMed : 11861389, PubMed : 17030238). Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1 (PubMed : 16327802).
Sequence similarities
Belongs to the type I cytokine receptor family. Type 5 subfamily.
Post-translational modifications
Cleaved by MMP8 leading to a soluble form that is also able to interact with IL13.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com