Recombinant Human IL-15RA protein is a Human Fragment protein, in the 31 to 130 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
I T C P P P M S V E H A D I W V K S Y S L Y S R E R Y I C N S G F K R K A G T S S L T E C V L N K A T N V A H W T T P S L K C I R D P A L V H Q R P A P P S T V T T A G V T P Q P E S L S P S G K E P A
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes (Recombinant protein). |
High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910). Isoform 5. Does not bind IL15. Isoform 6. Does not bind IL15. Isoform 7. Does not bind IL15. Isoform 8. Does not bind IL15.
CD215, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, IL15RA
Recombinant Human IL-15RA protein is a Human Fragment protein, in the 31 to 130 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
pH: 8
Constituents: 0.79% Tris HCl, 0.3% Glutathione
High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910).
N-glycosylated and O-glycosylated.
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ab114831 analyzed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.
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