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Recombinant Human IL-15RA protein is a Human Fragment protein, in the 31 to 130 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.

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Images

SDS-PAGE - Recombinant Human IL-15RA protein (AB114831), expandable thumbnail

Key facts

Expression system
Wheat germ
Tags
Tag free
Applications
SDS-PAGE, ELISA, WB
Biologically active
No

Amino acid sequence

I T C P P P M S V E H A D I W V K S Y S L Y S R E R Y I C N S G F K R K A G T S S L T E C V L N K A T N V A H W T T P S L K C I R D P A L V H Q R P A P P S T V T T A G V T P Q P E S L S P S G K E P A

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Application
ELISA
Reactivity
Reacts
Dilution info
-
Notes

-

Application
WB
Reactivity
Reacts
Dilution info
-
Notes

(Recombinant protein).

Target data

Function

High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910). Isoform 5. Does not bind IL15. Isoform 6. Does not bind IL15. Isoform 7. Does not bind IL15. Isoform 8. Does not bind IL15.

Alternative names

Recommended products

Recombinant Human IL-15RA protein is a Human Fragment protein, in the 31 to 130 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.

Key facts

Expression system
Wheat germ
Applications
SDS-PAGE, ELISA, WB
Accession
Q13261-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 8
Constituents: 0.79% Tris HCl, 0.3% Glutathione

Sequence info

Amino acid sequence

I T C P P P M S V E H A D I W V K S Y S L Y S R E R Y I C N S G F K R K A G T S S L T E C V L N K A T N V A H W T T P S L K C I R D P A L V H Q R P A P P S T V T T A G V T P Q P E S L S P S G K E P A
Accession
Q13261
Protein length
Fragment
Predicted molecular weight
36.63 kDa
Amino acids
31 to 130
Nature
Recombinant

Specifications

Form
Liquid

General info

Function

High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910).

Post-translational modifications

N-glycosylated and O-glycosylated.

Subcellular localisation
Nucleus membrane

Storage

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • SDS-PAGE - Recombinant Human IL-15RA protein (ab114831), expandable thumbnail

    SDS-PAGE - Recombinant Human IL-15RA protein (ab114831)

    ab114831 analyzed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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