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AB114831

Recombinant Human IL-15RA protein (GST tag N-Terminus)

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Recombinant Human IL-15RA protein (GST tag N-Terminus) is a Human Fragment protein, in the 31 to 130 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.

View Alternative Names

CD215, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, IL15RA

1 Images
SDS-PAGE - Recombinant Human IL-15RA protein (GST tag N-Terminus) (AB114831)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human IL-15RA protein (GST tag N-Terminus) (AB114831)

ab114831 analyzed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB, SDS-PAGE

applications

Biologically active

No

Accession

Q13261

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.3% Glutathione

storage-buffer

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Complementary Products

Proteins & Peptides

AB259403

Recombinant human IL-15 protein (Active)

Premium Bioactive

Functional Studies - Recombinant human IL-15 protein (Active) (AB259403)

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Primary Antibodies

AB273625

Anti-IL-15 antibody [EPR22635-214]

RabMAb|Recombinant

Immunoprecipitation - Anti-IL-15 antibody [EPR22635-214] (AB273625)

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Assay Kits

AB264618

Human IL-15RA ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human IL-15RA ELISA Kit (AB264618)

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Primary Antibodies

AB273022

Anti-IL-15RA antibody [EPR24784-142]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Flow Cytometry - Anti-IL-15RA antibody [EPR24784-142] (AB273022)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>(Recombinant protein).</p>" } } }
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Sequence info

[{"sequence":"ITCPPPMSVEHADIWVKSYSLYSRERYICNSGFKRKAGTSSLTECVLNKATNVAHWTTPSLKCIRDPALVHQRPAPPSTVTTAGVTPQPESLSPSGKEPA","proteinLength":"Fragment","predictedMolecularWeight":"36.63 kDa","actualMolecularWeight":null,"aminoAcidEnd":130,"aminoAcidStart":31,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q13261","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

High-affinity receptor for interleukin-15 (PubMed : 8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed : 15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed : 15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed : 10480910).. Isoform 5. Does not bind IL15.. Isoform 6. Does not bind IL15.. Isoform 7. Does not bind IL15.. Isoform 8. Does not bind IL15.

Post-translational modifications

N-glycosylated and O-glycosylated.. A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor (PubMed:15265897). It also binds IL-15 and thus interferes with IL-15 binding to the membrane receptor (PubMed:15265897).

Subcellular localisation

Nucleus membrane

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Product protocols

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Target data

High-affinity receptor for interleukin-15 (PubMed : 8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed : 15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed : 15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed : 10480910).. Isoform 5. Does not bind IL15.. Isoform 6. Does not bind IL15.. Isoform 7. Does not bind IL15.. Isoform 8. Does not bind IL15.
See full target information IL15RA
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Product promise

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