Recombinant Human IL-18BP protein (Fc Chimera His Tag) is a Human Full Length protein, in the 31 to 194 aa range, expressed in Baculovirus infected insect, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >90% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- Baculovirus infected insect cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
A D P T P V S Q T T T A A T A S V R S T K D P C P S Q P P V F P A A K Q C P A L E V T W P E V E V P L N G T L S L S C V A C S R F P N F S I L Y W L G N G S F I E H L P G R L W E G S T S R E R G S T G T Q L C K A L V L E Q L T P A L H S T N F S C V L V D P E Q V V Q R H V V L A Q L W A G L R A T L P P T Q E A L P S S H S S P Q Q Q G L E P K S C D K T H T C P P C P A P E L L G G P S V F L F P P K P K D T L M I S R T P E V T C V V V D V S H E D P E V K F N W Y V D G V E V H N A K T K P R E E Q Y N S T Y R V V S V L T V L H Q D W L N G K E Y K C K V S N K A L P A P I E K T I S K A K G Q P R E P Q V Y T L P P S R D E L T K N Q V S L T C L V K G F Y P S D I A V E W E S N G Q P E N N Y K T T P P V L D S D G S F F L Y S K L T V D K S R W Q Q G N V F S C S V M H E A L H N H Y T Q K S L S L S P G K H H H H H H
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
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Target data
Function
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Alternative names
Interleukin-18-binding protein, IL-18BP, Tadekinig-alfa, IL18BP
Recommended products
Recombinant Human IL-18BP protein (Fc Chimera His Tag) is a Human Full Length protein, in the 31 to 194 aa range, expressed in Baculovirus infected insect, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >90% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- Baculovirus infected insect cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- O95998-2
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: PBS, 10% Glycerol (glycerin, glycerine)
Sequence info
Amino acid sequence
- A D P T P V S Q T T T A A T A S V R S T K D P C P S Q P P V F P A A K Q C P A L E V T W P E V E V P L N G T L S L S C V A C S R F P N F S I L Y W L G N G S F I E H L P G R L W E G S T S R E R G S T G T Q L C K A L V L E Q L T P A L H S T N F S C V L V D P E Q V V Q R H V V L A Q L W A G L R A T L P P T Q E A L P S S H S S P Q Q Q G L E P K S C D K T H T C P P C P A P E L L G G P S V F L F P P K P K D T L M I S R T P E V T C V V V D V S H E D P E V K F N W Y V D G V E V H N A K T K P R E E Q Y N S T Y R V V S V L T V L H Q D W L N G K E Y K C K V S N K A L P A P I E K T I S K A K G Q P R E P Q V Y T L P P S R D E L T K N Q V S L T C L V K G F Y P S D I A V E W E S N G Q P E N N Y K T T P P V L D S D G S F F L Y S K L T V D K S R W Q Q G N V F S C S V M H E A L H N H Y T Q K S L S L S P G K H H H H H H
- Accession
- O95998
- Protein length
- Full Length
- Predicted molecular weight
- 44.9 kDa
- Amino acids
- 31 to 194
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Liquid
- Additional notes
Affinity purified
General info
- Function
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
- Post-translational modifications
N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); N-glycan at Asn-147: dHex1Hex5HexNAc4.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human IL-18BP protein (Fc Chimera His Tag) (ab222958)
15% SDS-PAGE analysis of 3 μg ab222958.
MWt 40-57 kDa (SDS-PAGE under reducing conditions) .
Downloads
Product protocols
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