Recombinant Human IL-18BP protein (His tag) is a Human Full Length protein, in the 31 to 194 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
T P V S Q T T T A A T A S V R S T K D P C P S Q P P V F P A A K Q C P A L E V T W P E V E V P L N G T L S L S C V A C S R F P N F S I L Y W L G N G S F I E H L P G R L W E G S T S R E R G S T G T Q L C K A L V L E Q L T P A L H S T N F S C V L V D P E Q V V Q R H V V L A Q L W A G L R A T L P P T Q E A L P S S H S S P Q Q Q G
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
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Target data
Function
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Alternative names
Interleukin-18-binding protein, IL-18BP, Tadekinig-alfa, IL18BP
Recommended products
Recombinant Human IL-18BP protein (His tag) is a Human Full Length protein, in the 31 to 194 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- O95998-2
- Animal free
- No
- Species
- Human
- Reconstitution
- Reconstitute at 400 µg/mL in water
- Concentration
- Storage buffer
pH: 7.4
Constituents: 95% PBS, 5% Trehalose
Sequence info
Amino acid sequence
- T P V S Q T T T A A T A S V R S T K D P C P S Q P P V F P A A K Q C P A L E V T W P E V E V P L N G T L S L S C V A C S R F P N F S I L Y W L G N G S F I E H L P G R L W E G S T S R E R G S T G T Q L C K A L V L E Q L T P A L H S T N F S C V L V D P E Q V V Q R H V V L A Q L W A G L R A T L P P T Q E A L P S S H S S P Q Q Q G
- Accession
- O95998
- Protein length
- Full Length
- Predicted molecular weight
- 18.5 kDa
- Amino acids
- 31 to 194
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
- Post-translational modifications
N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); N-glycan at Asn-147: dHex1Hex5HexNAc4.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Product promise
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human IL-18BP protein (His tag) (ab221201)
SDS-PAGE of reduced ab221201 stained overnight with Coomassie Blue. The protein migrates as 32-50 kDa in SDS-PAGE due to glycosylation.
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Product protocols
- Visit the general protocols
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