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AB191972

Recombinant Human IL-18R Beta/IL-18RAP protein

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Recombinant Human IL-18R Beta/IL-18RAP protein is a Human Fragment protein, in the 20 to 356 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, HPLC.

View Alternative Names

CD218b, IL1R7, IL18RAP, Interleukin-18 receptor accessory protein, IL-18 receptor accessory protein, IL-18RAcP, Accessory protein-like, CD218 antigen-like family member B, CDw218b, IL-1R accessory protein-like, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, AcPL, IL-1RAcPL, IL-1R-7, IL-1R7, IL-18R-beta, IL-18Rbeta

Key facts

Purity

>95% SDS-PAGE

Purity greater than 95% as determined by RP-HPLC and reducing SDS-PAGE.

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

HPLC, SDS-PAGE

applications

Biologically active

No

Accession

O95256

Animal free

No

Carrier free

No

Species

Human

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water.

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

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Complementary Products

Primary Antibodies

AB203191

Anti-IL-18R Beta/IL-18RAP antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-18R Beta/IL-18RAP antibody (AB203191)

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Proteins & Peptides

AB215030

Recombinant mouse IL-21R protein (Fc Chimera Active)

Bioactive

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Primary Antibodies

AB243091

Anti-IL-18 antibody [EPR19954-188]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-18 antibody [EPR19954-188] (AB243091)

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Proteins & Peptides

AB310799

Recombinant Human IL-18 Protein (His tag) (Active)

Premium Bioactive

Functional Studies - Recombinant Human IL-18 Protein (His tag) (Active) (AB310799)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as IL-18R Beta
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Sequence info

[{"linker":null,"sequence":"FNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRVDHHHHHH","proteinLength":"Fragment","predictedMolecularWeight":"39.48 kDa","actualMolecularWeight":null,"aminoAcidEnd":356,"aminoAcidStart":20,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"O95256","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Form
Lyophilized
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
A few weeks
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
False
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General info

Function

Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed : 14528293, PubMed : 25500532, PubMed : 9792649). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).

Sequence similarities

Belongs to the interleukin-1 receptor family.

Post-translational modifications

N-glycosylated.

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Product protocols

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Target data

Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed : 14528293, PubMed : 25500532, PubMed : 9792649). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
See full target information IL18RAP
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Product promise

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