Recombinant Human IL-21 protein
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Recombinant Human IL-21 protein is a Human Full Length protein, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE.
View Alternative Names
Interleukin-21, IL-21, Za11, IL21
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Lyophilized
Additional notes
Endotoxin: <0.1 ng/μg
General info
Function
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed : 11081504, PubMed : 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).
Sequence similarities
Belongs to the IL-15/IL-21 family.
Target data
Complementary Products
Product promise
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