Recombinant human IL-21R protein is a Human Fragment protein, in the 20 to 236 aa range, expressed in HEK 293, with >92% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
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Key facts
- Purity
- >92% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE, FuncS
- Biologically active
- Yes
Amino acid sequence
C P D L V C Y T D Y L Q T V I C I L E M W N L H P S T L T L T W Q D Q Y E E L K D E A T S C S L H R S A H N A T H A T Y T C H M D V F H F M A D D I F S V N I T D Q S G N Y S Q E C G S F L L A E S I K P A P P F N V T V T F S G Q Y N I S W R S D Y E D P A F Y M L K G K L Q Y E L Q Y R N R G D P W A V S P R R K L I S V D S R S V S L L P L E F R K D S S Y E L Q V R A G P M P G S S Y Q G T W S E W S D P V I F Q T Q S E E L K E G W N P
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
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Alternative names
CD360, NILR, UNQ3121/PRO10273, IL21R, Interleukin-21 receptor, IL-21 receptor, IL-21R, Novel interleukin receptor
Recommended products
Recombinant human IL-21R protein is a Human Fragment protein, in the 20 to 236 aa range, expressed in HEK 293, with >92% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
Key facts
- Purity
- >92% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE, FuncS
- Biologically active
- Yes
- Biological activity
- Measured by its ability to bind Human IL21 in a functional ELISA.
- Accession
- Q9HBE5-1
- Animal free
- No
- Species
- Human
- Reconstitution
- Reconstitute with sterile deionized water to a concentration of 200 µg/ml.
- Concentration
- Storage buffer
pH: 7.4
Constituents: 95% PBS, 5% Trehalose
Sequence info
Amino acid sequence
- C P D L V C Y T D Y L Q T V I C I L E M W N L H P S T L T L T W Q D Q Y E E L K D E A T S C S L H R S A H N A T H A T Y T C H M D V F H F M A D D I F S V N I T D Q S G N Y S Q E C G S F L L A E S I K P A P P F N V T V T F S G Q Y N I S W R S D Y E D P A F Y M L K G K L Q Y E L Q Y R N R G D P W A V S P R R K L I S V D S R S V S L L P L E F R K D S S Y E L Q V R A G P M P G S S Y Q G T W S E W S D P V I F Q T Q S E E L K E G W N P
- Accession
- Q9HBE5
- Protein length
- Fragment
- Predicted molecular weight
- 25.8 kDa
- Amino acids
- 20 to 236
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
This is a receptor for interleukin-21.
- Sequence similarities
Belongs to the type I cytokine receptor family. Type 4 subfamily.
- Post-translational modifications
C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -80°C
- Storage information
- Avoid freeze / thaw cycle, Reconstitute for long term storage
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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3 product images
SDS-PAGE - Recombinant human IL-21R protein (ab184891)
Human IL-21 R, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.
Functional Studies - Recombinant human IL-21R protein (ab184891)
Immobilized Biotinylated Human IL-21, Fc Tag at 2 µg/mL (100 µL/well) can bind Human IL-21 R, His Tag with a linear range of 2-8 ng/mL.
SDS-PAGE - Recombinant human IL-21R protein (ab184891)
SDS-PAGE analysis ab184891 stained overnight with Coomassie Blue.
DTT-reduced Protein migrates as 42-50 kDa due to glycosylation.
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