Recombinant Human IL-29 protein
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Recombinant Human IL-29 protein is a Human Fragment protein, in the 22 to 200 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
View Alternative Names
IL29, ZCYTO21, IFNL1, Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, Interleukin-29, IL-29
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human IL-29 protein (AB256025)
SDS-PAGE analysis of ab256025 (1μg) under reducing (Lane 1) and non-reducing (Lane 2) conditions.
Human IL-29 is predicted to have a MW of 19.9kDa.
4-20% Tris-Glycine gel. Coomassie Blue staining.
Complementary Products
Reactivity data
Sequence info
Properties and storage information
Form
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
General info
Function
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets : is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Sequence similarities
Belongs to the type-III (or lambda) interferon family.
Target data
Product promise
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