Recombinant Human IL-29 protein (denatured)
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Recombinant Human IL-29 protein (denatured) is a Human Full Length protein, in the 20 to 200 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
View Alternative Names
IL29, ZCYTO21, IFNL1, Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, Interleukin-29, IL-29
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human IL-29 protein (denatured) (AB202252)
15% SDS-PAGE analysis of ab202252 (3 μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets : is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Sequence similarities
Belongs to the lambda interferon family.
Target data
Complementary Products
Product promise
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