JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB288525

Recombinant Human IL-34 protein (Active)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human IL-34 protein (Active) is a Human Full Length protein, in the 21 to 242 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, Mass Spec, HPLC, Cell Culture.

View Alternative Names

C16orf77, IL34, Interleukin-34, IL-34

4 Images
Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)

ESI TOF analysis of ab288525.

Predicted MW is 25289.0 Da (+/- 10 Da by ESI TOF). Observed MW is25290.13

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)
  • FuncS

Supplier Data

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)
  • HPLC

Supplier Data

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)

HPLC analysis of ab288525.

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)

SDS-PAGE analysis of ab288525.

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

<0.005 EU/µg

Expression system

HEK 293 cells

Tags

Tag free

Applications

Mass Spec, HPLC, Cell Culture, FuncS, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

Accession

Q6ZMJ4

Animal free

Yes

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

Storage buffer

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

style
left-column

Complementary Products

Reagents, Controls & Accessories

AB313995

Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa) (AB313995)

  • 0
  • 0
Proteins & Peptides

AB259396

Recombinant human M-CSF protein (Active)

Premium Bioactive

Mass Spectrometry - Recombinant human M-CSF protein (Active) (AB259396)

  • 0
  • 0
Proteins & Peptides

AB50036

Recombinant human TGF beta 1 protein (Active)

Bioactive

  • 0
  • 0
Proteins & Peptides

AB259381

Recombinant human IL-6 protein (Active)

Premium Bioactive

Functional Studies (Neut/Block) - Recombinant human IL-6 protein (Active) (AB259381)

  • 5
  • 1
Proteins & Peptides

AB259403

Recombinant human IL-15 protein (Active)

Premium Bioactive

Functional Studies - Recombinant human IL-15 protein (Active) (AB259403)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Cell Culture": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"NEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVETLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLP","proteinLength":"Full Length","predictedMolecularWeight":"25.29 kDa","actualMolecularWeight":"25.9 kDa","aminoAcidEnd":242,"aminoAcidStart":21,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6ZMJ4","tags":[]}]
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
True
style
left-column
style
left-column

Specifications

Form

Lyophilized

Additional notes

Purity by HPLC =95%

style
left-column

General info

Function

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

Sequence similarities

Belongs to the IL-34 family.

style
left-column

Product protocols

style
left-column

Target data

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
See full target information IL34
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com