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AB132052

Recombinant Human IL-9R protein (GST tag N-Terminus)

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Recombinant Human IL-9R protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 332 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.

View Alternative Names

CD129, Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9R

1 Images
SDS-PAGE - Recombinant Human IL-9R protein (GST tag N-Terminus) (AB132052)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human IL-9R protein (GST tag N-Terminus) (AB132052)

12.5% SDS-PAGE analysis of ab132052 stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

SDS-PAGE, WB, ELISA

applications

Biologically active

No

Accession

Q01113

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MHLGSNCCKNGQTLLQRTCHGVSCCGWWFQAARSILGKGPSAQSLAGWTLESEALRRDMGTWLLACICICTCVCLGVSVTGEGQGPRSRTFTCLTNNILRIDCHWSAPELGQGSSPWLLFTRLLAAHISASCGAVSAPSCCHLRQCSCHLTISPSLSTTACLGGSRSAWWTRSTCPGDTSNISSGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRLGWGPTGPVCC","proteinLength":"Full Length","predictedMolecularWeight":"62.26 kDa","actualMolecularWeight":null,"aminoAcidEnd":332,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q01113","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Interleukin 9 receptor (IL-9R) also known as CD129 is a transmembrane protein that belongs to the cytokine receptor family. It weighs approximately 54 kDa. IL-9R is expressed on various cell types including T cells B cells mast cells and certain epithelial cells. This receptor primarily binds to interleukin 9 (IL-9) and forms a heterodimer with the common gamma chain a component shared with other interleukin receptors.
Biological function summary

IL-9R plays essential roles in immune system signaling and regulation. As part of a receptor complex it activates downstream signaling pathways upon IL-9 binding influencing the immune responses such as cell survival proliferation and differentiation. IL-9R is also known to modulate allergic inflammation and has effects on both innate and adaptive immune responses.

Pathways

Research indicates that IL-9R is a participant in the JAK/STAT signaling pathway. This pathway includes janus kinase 1 (JAK1) and signal transducer and activator of transcription 5 (STAT5) both important for transmitting signals from IL-9 to exert cellular effects. IL-9R also connects to pathways involving other immune-modulating interleukins suggesting its broad role in immune regulation.

IL-9R holds a significant relationship with asthma and allergic diseases. It plays a role in promoting inflammatory responses in the airways related to conditions like asthma. Moreover IL-9R has connections with IL-13 in the context of allergic inflammation and this interaction may amplify disease pathology. Understanding the dynamics of IL-9R could offer insights into therapeutic targets for managing such immune-related disorders.
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Specifications

Form

Liquid

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General info

Function

Plays an important role in the immune response against parasites by acting as a receptor of IL9.

Sequence similarities

Belongs to the type I cytokine receptor family. Type 4 subfamily.

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Product protocols

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Target data

Plays an important role in the immune response against parasites by acting as a receptor of IL9.
See full target information IL9R
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Product promise

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