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Recombinant Human ILT-3 protein (Tagged) is a Human Fragment protein, in the 17 to 257 aa range, expressed in HEK 293, with >=90% purity and suitable for SDS-PAGE.
Alternative names=Leukocyte immunoglobulin-like receptor subfamily B member 4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, Leukocyte immunoglobulin-like receptor 5, Monocyte inhibitory receptor HM18, ILT-3, LIR-5, LILRB4, ILT3, LIR5
- Purity
>=90% SDS-PAGE
- Expression system
HEK 293 cells
- Tags
Avi tag C-Terminus, His tag C-Terminus
- Applications
SDS-PAGE
- Biologically active
No
- Sequence
P R T H M Q A G P L P K P T L W A E P G S V I S W G N S V T I W C Q G T L E A R E Y R L D K E E S P A P W D R Q N P L E P K N K A R F S I P S M T E D Y A G R Y R C Y Y R S P V G W S Q P S D P L E L V M T G A Y S K P T L S A L P S P L V T S G K S V T L L C Q S R S P M D T F L L I K E R A A H P L L H L R S E H G A Q Q H Q A E F P M S P V T S V H G G T Y R C F S S H G F S H Y L L S H P S D P L E L I V S G S L E D P R P S P T R S V S T A A G P E D Q P L M P T G S V P H S G L R R H W E V L I G V L V V S I L L L S L L L F L L L Q H W R Q G K H R T L A Q R Q A D F Q R P P G A A E P E P K D G G L Q R R S S P A A D V Q G E N F C A A V K N T Q P E D G V E M D T R Q S P H D E D P Q A
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Images
Target data
Function
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
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Recombinant Human ILT-3 protein (Tagged) is a Human Fragment protein, in the 17 to 257 aa range, expressed in HEK 293, with >=90% purity and suitable for SDS-PAGE.
Alternative names=Leukocyte immunoglobulin-like receptor subfamily B member 4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, Leukocyte immunoglobulin-like receptor 5, Monocyte inhibitory receptor HM18, ILT-3, LIR-5, LILRB4, ILT3, LIR5
Key facts
- Purity
>=90% SDS-PAGE
- Expression system
HEK 293 cells
- Tags
Avi tag C-Terminus, His tag C-Terminus
- Applications
SDS-PAGE
- Biologically active
No
- Predicted molecular weight
31 kDa
- Amino acids
17 to 257
- Sequence
P R T H M Q A G P L P K P T L W A E P G S V I S W G N S V T I W C Q G T L E A R E Y R L D K E E S P A P W D R Q N P L E P K N K A R F S I P S M T E D Y A G R Y R C Y Y R S P V G W S Q P S D P L E L V M T G A Y S K P T L S A L P S P L V T S G K S V T L L C Q S R S P M D T F L L I K E R A A H P L L H L R S E H G A Q Q H Q A E F P M S P V T S V H G G T Y R C F S S H G F S H Y L L S H P S D P L E L I V S G S L E D P R P S P T R S V S T A A G P E D Q P L M P T G S V P H S G L R R H W E V L I G V L V V S I L L L S L L L F L L L Q H W R Q G K H R T L A Q R Q A D F Q R P P G A A E P E P K D G G L Q R R S S P A A D V Q G E N F C A A V K N T Q P E D G V E M D T R Q S P H D E D P Q A
- Accession
- Q8NHJ6-1
- Protein length
Fragment
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.13% Sodium phosphate, 0.02% Potassium chloride
Specifications
- Form
Liquid
General info
- Function
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Storage
- Shipped at conditions
Dry Ice
- Appropriate long-term storage conditions
-80°C
- Storage information
Avoid freeze / thaw cycle
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