JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB276664

Recombinant Human INSL6 protein (His tag)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human INSL6 protein (His tag) is a Human Fragment protein, in the 1 to 198 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

RIF1, INSL6, Insulin-like peptide INSL6, Insulin-like peptide 6, Relaxin/insulin-like factor 1

1 Images
SDS-PAGE - Recombinant Human INSL6 protein (His tag) (AB276664)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human INSL6 protein (His tag) (AB276664)

SDS-PAGE analysis of ab276664

Key facts

Purity

>90% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q9Y581

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

style
left-column

Complementary Products

Proteins & Peptides

AB183259

Recombinant Human TSR2 protein

  • 0
  • 0
Proteins & Peptides

AB181920

Recombinant Human TRBP protein (denatured)

  • 0
  • 0
Proteins & Peptides

AB276695

Recombinant Human TECTB protein (His tag)

  • 0
  • 0
Proteins & Peptides

AB276503

Recombinant Human SLITRK4 protein (His tag)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MPRLLRLSLLWLGLLLVRFSRELSDISSARKLCGRYLVKEIEKLCGHANWSQFRFEEETPFSRLIAQASEKVEAYSPYQFESPQTASPARGRGTNPVSTSWEEAVNSWEMQSLPEYKDKKGYSPLGKTREFSSSHNINVYIHENAKFQKKRRNKIKTLSNLFWGHHPQRKRRGYSEKCCLTGCTKEELSIACLPYIDF","proteinLength":"Fragment","predictedMolecularWeight":"22.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":198,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q9Y581","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

INSL6 also known as Insulin-like peptide 6 is a protein involved in several physiological processes. It belongs to the insulin superfamily and has a molecular mass of approximately 12 kDa. Researchers find its expression mainly in the testis but it also appears in other tissues like the placenta. INSL6 plays a role in male reproductive physiology reflecting its expression and function.
Biological function summary

The functions of INSL6 involve reproductive health and fertility. It does not currently appear to form part of a larger protein complex. Studies suggest its involvement in spermatogenesis the process of sperm cell development. INSL6 impacts the proliferation and differentiation of germ cells. These functions highlight its role in maintaining male fertility.

Pathways

INSL6 interacts with processes connected to male reproductive health. It may influence the cyclic adenosine monophosphate (cAMP) signaling pathway which is important in numerous cellular responses. The protein INSL3 another member of the insulin superfamily associates with some similar pathways and shares functional parallels with INSL6 in reproductive biology. These pathways indicate its role in regulatory mechanisms influencing reproduction.

Research links INSL6 to male infertility. Mutations or abnormal expression levels may contribute to testicular dysfunction affecting spermatogenesis adversely. While studies continue another related protein relaxin may show therapeutic potential in similar reproductive disorders. The connection of INSL6 to these conditions emphasizes its importance in understanding and potentially treating male infertility.
style
left-column

Specifications

Form

Lyophilized

style
left-column

General info

Function

May have a role in sperm development and fertilization.

Sequence similarities

Belongs to the insulin family.

style
left-column

Product protocols

style
left-column

Target data

May have a role in sperm development and fertilization.
See full target information INSL6
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com