Recombinant Human Interferon alpha 2b protein (Tag Free)
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(1 Publication)
Recombinant Human Interferon alpha 2b protein (Tag Free) is a Human Fragment protein, in the 24 to 188 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, WB.
View Alternative Names
IFNA2A, IFNA2B, IFNA2C, IFNA2, Interferon alpha-2, IFN-alpha-2, Interferon alpha-A, LeIF A
- WB
Unknown
Western blot - Recombinant Human Interferon alpha 2b protein (Tag Free) (AB51094)
All lanes:
Western blot - Anti-Interferon alpha 2b antibody [24B10] (<a href='/en-us/products/primary-antibodies/interferon-alpha-2b-antibody-24b10-ab87900'>ab87900</a>) at 5 µg/mL
All lanes:
Western blot - Recombinant Human Interferon alpha 2b protein (Tag Free) (ab51094) at 0.01 µg
Secondary
All lanes:
Western blot - Goat Anti-Mouse IgG H&L (HRP) preadsorbed (<a href='/en-us/products/secondary-antibodies/goat-mouse-igg-h-l-hrp-preadsorbed-ab97040'>ab97040</a>) at 1/5000 dilution
Predicted band size: 22 kDa
true
Exposure time: 1min
- WB
Unknown
Western blot - Recombinant Human Interferon alpha 2b protein (Tag Free) (AB51094)
All lanes:
Western blot - Anti-Interferon alpha 2b antibody [24B10] (<a href='/en-us/products/primary-antibodies/interferon-alpha-2b-antibody-24b10-ab87900'>ab87900</a>) at 5 µg/mL
All lanes:
Western blot - Recombinant Human Interferon alpha 2b protein (Tag Free) (ab51094) at 0.01 µg
Secondary
All lanes:
Western blot - Goat Anti-Mouse IgG H&L (HRP) preadsorbed (<a href='/en-us/products/secondary-antibodies/goat-mouse-igg-h-l-hrp-preadsorbed-ab97040'>ab97040</a>) at 1/5000 dilution
Predicted band size: 22 kDa
true
Exposure time: 1min
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Interferon alpha 2b protein (Tag Free) (AB51094)
ab51094 in 15% SDS-PAGE
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Interferon alpha 2b stimulates the immune system to attack pathogens by enhancing antigen presentation and activating natural killer cells and macrophages. It does not function as part of a complex and it acts independently to initiate an antiviral state in cells and increase the host's defense mechanisms. Its role in regulating cell growth and differentiation adds to its importance in maintaining immune homeostasis.
Pathways
Interferon alpha 2b is involved in the JAK-STAT signaling pathway which induces transcription of interferon-stimulated genes that orchestrate an immune response. Additionally it plays a role in the interferon signaling pathway which contributes to innate immunity. Proteins related to it through these pathways include STAT1 and STAT2 which collaborate with IFN alpha-b protein to transmit signals from extracellular stimuli to the nucleus resulting in gene activation.
Specifications
Form
Liquid
Additional notes
Interferon alpha 2b was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
General info
Function
Produced by macrophages, IFN-alpha have antiviral activities.
Sequence similarities
Belongs to the alpha/beta interferon family.
Target data
Publications (1)
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Applied microbiology and biotechnology 108:229 PubMed38393430
2024
Applications
Unspecified application
Species
Unspecified reactive species
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