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AB127810

Recombinant Human KCTD17 protein (His-DHFR tag N-Terminus)

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Recombinant Human KCTD17 protein (His-DHFR tag N-Terminus) is a Human Fragment protein, in the 67 to 230 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE.

View Alternative Names

BTB/POZ domain-containing protein KCTD17, KCTD17

Key facts

Purity

>95%

Expression system

Escherichia coli

Tags

His-DHFR tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q8N5Z5

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in water

Storage buffer

Constituents: 0.58% Sodium chloride, 0.32% Tris HCl

storage-buffer

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Complementary Products

Primary Antibodies

AB169624

Anti-KCTD17 antibody

Immunocytochemistry/ Immunofluorescence - Anti-KCTD17 antibody (AB169624)

  • 0
  • 0
Reagents, Controls & Accessories

AB119211

InstantBlue® Coomassie Protein Stain (ISB1L)

Western blot - InstantBlue® Coomassie Protein Stain (ISB1L) (AB119211)

  • 5
  • 5
Proteins & Peptides

AB187472

Recombinant Human Elp4 protein (denatured) (His tag N-Terminus)

SDS-PAGE - Recombinant Human Elp4 protein (denatured) (AB187472)

  • 0
  • 0
Proteins & Peptides

AB153599

Recombinant Human SESN3 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human SESN3 protein (GST tag N-Terminus) (AB153599)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":"19 kDa","actualMolecularWeight":null,"aminoAcidEnd":230,"aminoAcidStart":67,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q8N5Z5","tags":[{"tag":"His-DHFR","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Lyophilized

Additional notes

Purity determined to be >95% by SDS-PAGE.

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General info

Function

Substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediates the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. Thereby, positively regulates ciliogenesis, playing a crucial role in the initial steps of axoneme extension (PubMed : 25270598). May also play a role in endoplasmic reticulum calcium ion homeostasis (PubMed : 25983243).

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Product protocols

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Target data

Substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediates the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. Thereby, positively regulates ciliogenesis, playing a crucial role in the initial steps of axoneme extension (PubMed : 25270598). May also play a role in endoplasmic reticulum calcium ion homeostasis (PubMed : 25983243).
See full target information KCTD17
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Product promise

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For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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