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AB127809

Recombinant Human KDELC1 protein

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Recombinant Human KDELC1 protein is a Human Fragment protein, in the 326 to 494 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE.

View Alternative Names

EP58, KDELC1, UNQ1910/PRO4357, POGLUT2, Protein O-glucosyltransferase 2, Endoplasmic reticulum resident protein 58, KDEL motif-containing protein 1, Protein O-xylosyltransferase POGLUT2, ER protein 58, ERp58

Key facts

Purity

>95%

Expression system

Escherichia coli

Tags

His-DHFR tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q6UW63

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in water

Storage buffer

Constituents: 0.58% Sodium chloride, 0.32% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":"20.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":494,"aminoAcidStart":326,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q6UW63","tags":[{"tag":"His-DHFR","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Lyophilized

Additional notes

Purity determined to be >95% by SDS-PAGE.

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General info

Function

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed : 30127001). Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed : 30127001). Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1 (PubMed : 30127001, PubMed : 34411563). May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed : 30127001).

Sequence similarities

Belongs to the KDELC family.

Post-translational modifications

N-glycosylated.

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Product protocols

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Target data

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed : 30127001). Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed : 30127001). Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1 (PubMed : 30127001, PubMed : 34411563). May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed : 30127001).
See full target information POGLUT2
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Product promise

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