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AB167940

Recombinant Human KDM4C / GASC1 / JMJD2C protein

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(2 Publications)

Recombinant Human KDM4C / GASC1 / JMJD2C protein is a Human Fragment protein, in the 1 to 460 aa range, expressed in Baculovirus infected Sf9 cells, with >95%, suitable for SDS-PAGE, WB.

View Alternative Names

GASC1, JHDM3C, JMJD2C, KIAA0780, KDM4C, Lysine-specific demethylase 4C, Gene amplified in squamous cell carcinoma 1 protein, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, [histone H3]-trimethyl-L-lysine(9) demethylase 4C, GASC-1 protein

1 Images
SDS-PAGE - Recombinant Human KDM4C / GASC1 / JMJD2C protein (AB167940)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human KDM4C / GASC1 / JMJD2C protein (AB167940)

SDS Page analysis of ab167940

Key facts

Purity

>95% Densitometry

Expression system

Baculovirus infected Sf9 cells

Tags

GST tag N-Terminus

Applications

WB, SDS-PAGE

applications

Biologically active

No

Accession

Q9H3R0

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.79% Tris HCl, 0.31% Glutathione, 0.29% Sodium chloride, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.004% EDTA, 0.002% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSV","proteinLength":"Fragment","predictedMolecularWeight":"82 kDa","actualMolecularWeight":null,"aminoAcidEnd":460,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Baculovirus infected Sf9 cells","accessionNumber":"Q9H3R0","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

Affinity purified.

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General info

Function

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Sequence similarities

Belongs to the JHDM3 histone demethylase family.

Subcellular localisation

Nucleus

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Product protocols

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Target data

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
See full target information KDM4C
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Theranostics 10:6095-6112 PubMed32483441

2020

Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Tsai-Tsen Liao,Chun-Chi Lin,Jeng-Kae Jiang,Shung-Haur Yang,Hao-Wei Teng,Muh-Hwa Yang

Proceedings of the National Academy of Sciences of 111:9235-40 PubMed24928520

2014

Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens.

Applications

WB

Species

Unspecified reactive species

Chunyu Jin,Liuqing Yang,Min Xie,Chunru Lin,Daria Merkurjev,Joy C Yang,Bogdan Tanasa,Soohwan Oh,Jie Zhang,Kenneth A Ohgi,Hongyan Zhou,Wenbo Li,Christopher P Evans,Sheng Ding,Michael G Rosenfeld
View all publications
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Complementary Products

Primary Antibodies

AB38113

Anti-KDM6B / JMJD3 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KDM6B / JMJD3 antibody (AB38113)

  • 3
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Primary Antibodies

AB182858

Anti-Bcl-2 antibody [EPR17509]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bcl-2 antibody [EPR17509] (AB182858)

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Primary Antibodies

AB32503

Anti-Bax antibody [E63]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bax antibody [E63] (AB32503)

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Proteins & Peptides

AB198159

Recombinant human KDM4B / JMJD2B protein

Functional Studies - Recombinant human KDM4B / JMJD2B protein (AB198159)

  • 0
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