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Recombinant Human KDM4C / GASC1 / JMJD2C protein is a Human Fragment protein, in the 1 to 460 aa range, expressed in Baculovirus infected Sf9, with >95% purity and suitable for SDS-PAGE, WB.

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SDS-PAGE - Recombinant Human KDM4C / GASC1 / JMJD2C protein (AB167940), expandable thumbnail

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Key facts

Purity
>95% Densitometry
Expression system
Baculovirus infected Sf9 cells
Tags
GST tag N-Terminus
Applications
SDS-PAGE, WB
Biologically active
No

Amino acid sequence

M E V A E V E S P L N P S C K I M T F R P S M E E F R E F N K Y L A Y M E S K G A H R A G L A K V I P P K E W K P R Q C Y D D I D N L L I P A P I Q Q M V T G Q S G L F T Q Y N I Q K K A M T V K E F R Q L A N S G K Y C T P R Y L D Y E D L E R K Y W K N L T F V A P I Y G A D I N G S I Y D E G V D E W N I A R L N T V L D V V E E E C G I S I E G V N T P Y L Y F G M W K T T F A W H T E D M D L Y S I N Y L H F G E P K S W Y A I P P E H G K R L E R L A Q G F F P S S S Q G C D A F L R H K M T L I S P S V L K K Y G I P F D K I T Q E A G E F M I T F P Y G Y H A G F N H G F N C A E S T N F A T V R W I D Y G K V A K L C T C R K D M V K I S M D I F V R K F Q P D R Y Q L W K Q G K D I Y T I D H T K P T P A S T P E V K A W L Q R R R K V R K A S R S F Q C A R S T S K R P K A D E E E E V S D E V D G A E V P N P D S V T D D L K V S E K S E A A V K L R N T E A S S E E E S S A S R M Q V E Q N L S D H I K L S G N S C L S T S V

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Application
WB
Reactivity
Reacts
Dilution info
-
Notes

-

Associated Products

Select an associated product type

1 product for Alternative Product

Target data

Function

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Alternative names

GASC1, JHDM3C, JMJD2C, KIAA0780, KDM4C, Lysine-specific demethylase 4C, Gene amplified in squamous cell carcinoma 1 protein, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, [histone H3]-trimethyl-L-lysine(9) demethylase 4C, GASC-1 protein

Recommended products

Recombinant Human KDM4C / GASC1 / JMJD2C protein is a Human Fragment protein, in the 1 to 460 aa range, expressed in Baculovirus infected Sf9, with >95% purity and suitable for SDS-PAGE, WB.

Key facts

Purity
>95% Densitometry
Expression system
Baculovirus infected Sf9 cells
Applications
SDS-PAGE, WB
Accession
Q9H3R0-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 7.5
Constituents: 25% Glycerol (glycerin, glycerine), 0.79% Tris HCl, 0.31% Glutathione, 0.29% Sodium chloride, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.004% EDTA, 0.002% PMSF

Sequence info

Amino acid sequence

M E V A E V E S P L N P S C K I M T F R P S M E E F R E F N K Y L A Y M E S K G A H R A G L A K V I P P K E W K P R Q C Y D D I D N L L I P A P I Q Q M V T G Q S G L F T Q Y N I Q K K A M T V K E F R Q L A N S G K Y C T P R Y L D Y E D L E R K Y W K N L T F V A P I Y G A D I N G S I Y D E G V D E W N I A R L N T V L D V V E E E C G I S I E G V N T P Y L Y F G M W K T T F A W H T E D M D L Y S I N Y L H F G E P K S W Y A I P P E H G K R L E R L A Q G F F P S S S Q G C D A F L R H K M T L I S P S V L K K Y G I P F D K I T Q E A G E F M I T F P Y G Y H A G F N H G F N C A E S T N F A T V R W I D Y G K V A K L C T C R K D M V K I S M D I F V R K F Q P D R Y Q L W K Q G K D I Y T I D H T K P T P A S T P E V K A W L Q R R R K V R K A S R S F Q C A R S T S K R P K A D E E E E V S D E V D G A E V P N P D S V T D D L K V S E K S E A A V K L R N T E A S S E E E S S A S R M Q V E Q N L S D H I K L S G N S C L S T S V
Accession
Q9H3R0
Protein length
Fragment
Predicted molecular weight
82 kDa
Amino acids
1 to 460
Nature
Recombinant
Tags
GST tag N-Terminus

Specifications

Form
Liquid
Additional notes

Affinity purified.

General info

Function

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Sequence similarities

Belongs to the JHDM3 histone demethylase family.

Subcellular localisation
Nucleus

Storage

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product promise

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1 product image

  • SDS-PAGE - Recombinant Human KDM4C / GASC1 / JMJD2C protein (ab167940), expandable thumbnail

    SDS-PAGE - Recombinant Human KDM4C / GASC1 / JMJD2C protein (ab167940)

    SDS Page analysis of ab167940

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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