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AB51218

Recombinant Human KIR3DL1 protein (His tag N-Terminus)

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Recombinant Human KIR3DL1 protein (His tag N-Terminus) is a Human Fragment protein, in the 361 to 444 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE.

View Alternative Names

CD158e, CD158E, NKAT3, NKB1, KIR3DL1, Killer cell immunoglobulin-like receptor 3DL1, CD158 antigen-like family member E, HLA-BW4-specific inhibitory NK cell receptor, Natural killer-associated transcript 3, p70 natural killer cell receptor clones CL-2/CL-11, NKAT-3, p70 NK receptor CL-2/CL-11

1 Images
SDS-PAGE - Recombinant Human KIR3DL1 protein (His tag N-Terminus) (AB51218)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human KIR3DL1 protein (His tag N-Terminus) (AB51218)

14% SDS-PAGE gel loaded with ab51218, recombinant human KIR3DL1 protein (His tag).
Predicted molecular weight 15kDa.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P43629

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 0.58% Sodium chloride, 0.395% Tris HCl

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Product details

The cytoplasmic tail of KIR3DL1, which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity.

Sequence info

[{"sequence":"MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSTSGTIDKLDIEFHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP","proteinLength":"Fragment","predictedMolecularWeight":"15 kDa","actualMolecularWeight":null,"aminoAcidEnd":444,"aminoAcidStart":361,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P43629","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Specifications

Form

Liquid

Additional notes

A His-tag fusion protein of KIR3DL1 cytoplasmic tail was overexpressed as insoluble protein aggregates (inclusion bodies). This protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.

General info

Function

Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.

Sequence similarities

Belongs to the immunoglobulin superfamily.

Product protocols

Target data

Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.
See full target information KIR3DL1

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