Recombinant Human KIR3DL1 protein is a Human Fragment protein, in the 361 to 444 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M R G S H H H H H H G M A S M T G G Q Q M G R D L Y D D D D K D R W G S T S G T I D K L D I E F H L W C S N K K N A A V M D Q E P A G N R T A N S E D S D E Q D P E E V T Y A Q L D H C V F T Q R K I T R P S Q R P K T P P T D T I L Y T E L P N A K P R S K V V S C P
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.
Alternative names
CD158e, CD158E, NKAT3, NKB1, KIR3DL1, Killer cell immunoglobulin-like receptor 3DL1, CD158 antigen-like family member E, HLA-BW4-specific inhibitory NK cell receptor, Natural killer-associated transcript 3, p70 natural killer cell receptor clones CL-2/CL-11, NKAT-3, p70 NK receptor CL-2/CL-11
Recommended products
Recombinant Human KIR3DL1 protein is a Human Fragment protein, in the 361 to 444 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- P43629-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.5
Constituents: 0.58% Sodium chloride, 0.395% Tris HCl
Sequence info
Amino acid sequence
- M R G S H H H H H H G M A S M T G G Q Q M G R D L Y D D D D K D R W G S T S G T I D K L D I E F H L W C S N K K N A A V M D Q E P A G N R T A N S E D S D E Q D P E E V T Y A Q L D H C V F T Q R K I T R P S Q R P K T P P T D T I L Y T E L P N A K P R S K V V S C P
- Accession
- P43629
- Protein length
- Fragment
- Predicted molecular weight
- 15 kDa
- Amino acids
- 361 to 444
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
A His-tag fusion protein of KIR3DL1 cytoplasmic tail was overexpressed as insoluble protein aggregates (inclusion bodies). This protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.
General info
- Function
Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.
- Sequence similarities
Belongs to the immunoglobulin superfamily.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
The cytoplasmic tail of KIR3DL1, which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity.
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1 product image
SDS-PAGE - Recombinant Human KIR3DL1 protein (ab51218)
14% SDS-PAGE gel loaded with ab51218, recombinant human KIR3DL1 protein (His tag).
Predicted molecular weight 15kDa.
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Product protocols
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