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Recombinant Human LGALS3 Protein (His-tag) is a Human Full Length protein, expressed in Escherichia coli, with >=95% purity and suitable for HPLC, MS.
Alternative names=Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, CBP 35, GALBP, LGALS3, MAC2
- Purity
>=95% HPLC
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
HPLC, MS
- Biologically active
No
- Mass spectrometry
LC-MS/MS
- Actual molecular weight
27.21 kDa
- Sequence
M A D N F S L H D A L S G S G N P N P Q G W P G A W G N Q P A G A G G Y P G A S Y P G A Y P G Q A P P G A Y P G Q A P P G A Y P G A P G A Y P G A P A P G V Y P G P P S G P G A Y P S S G Q P S A T G A Y P A T G P Y G A P A G P L I V P Y N L P L P G G V V P R M L I T I L G T V K P N A N R I A L D F Q R G N D V A F H F N P R F N E N N R R V I V C N T K L D N N W G R E E R Q S V F P F E S G K P F K I Q V L V E P D H F K V A V N D A H L L Q Y N H R V K K L N E I S K L G I S G D I D L T S A S Y T M I
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application HPLC | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Images
Target data
Function
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
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Recombinant Human LGALS3 Protein (His-tag) is a Human Full Length protein, expressed in Escherichia coli, with >=95% purity and suitable for HPLC, MS.
Alternative names=Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, CBP 35, GALBP, LGALS3, MAC2
Key facts
- Purity
>=95% HPLC
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
HPLC, MS
- Biologically active
No
- Mass spectrometry
LC-MS/MS
- Predicted molecular weight
27.34 kDa
- Actual molecular weight
27.21 kDa
- Sequence
M A D N F S L H D A L S G S G N P N P Q G W P G A W G N Q P A G A G G Y P G A S Y P G A Y P G Q A P P G A Y P G Q A P P G A Y P G A P G A Y P G A P A P G V Y P G P P S G P G A Y P S S G Q P S A T G A Y P A T G P Y G A P A G P L I V P Y N L P L P G G V V P R M L I T I L G T V K P N A N R I A L D F Q R G N D V A F H F N P R F N E N N R R V I V C N T K L D N N W G R E E R Q S V F P F E S G K P F K I Q V L V E P D H F K V A V N D A H L L Q Y N H R V K K L N E I S K L G I S G D I D L T S A S Y T M I
- Accession
- P17931-1
- Protein length
Full Length
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.4862% Sodium chloride, 0.3752% Tris HCl
Specifications
- Form
Liquid
General info
- Function
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
- Subcellular localisation
Nucleus
Storage
- Shipped at conditions
Dry Ice
- Appropriate short-term storage conditions
-80°C
- Appropriate long-term storage conditions
-80°C
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