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AB276713

Recombinant Human LILRA5 protein (His tag)

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Recombinant Human LILRA5 protein (His tag) is a Human Fragment protein, in the 1 to 268 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

CD85f, ILT11, LILRB7, LIR9, LILRA5, Leukocyte immunoglobulin-like receptor subfamily A member 5, CD85 antigen-like family member F, Immunoglobulin-like transcript 11, Leukocyte immunoglobulin-like receptor 9, ILT-11, LIR-9

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SDS-PAGE - Recombinant Human LILRA5 protein (His tag) (AB276713)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human LILRA5 protein (His tag) (AB276713)

SDS-PAGE analysis of ab276713

Key facts

Purity

>95% HPLC

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

A6NI73

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MAPWSHPSAQLQPVGGDAVSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIR","proteinLength":"Fragment","predictedMolecularWeight":"26.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":268,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"A6NI73","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The protein known as LILRA5 also referred to as ILT11 serves as a receptor on myeloid cells. It possesses an approximate molecular mass of 46 kDa. LILRA5 is expressed mainly on monocytes and macrophages playing an important role in the immune response. Its function involves the recognition and binding of specific ligand molecules which consequently initiates intracellular signaling pathways that modulate immune cell activity.
Biological function summary

LILRA5 influences the regulation of the immune system through its interaction with ligands such as pathogen-associated molecules. It participates in myeloid cell activation promoting pro-inflammatory responses. This receptor does not operate in isolation; instead it functions as part of a complex network of receptors and signaling molecules that contribute to frontline defense mechanisms. LILRA5's presence heightens the immune system's ability to recognize and respond to pathogenic threats effectively.

Pathways

LILRA5 is involved in the regulation and modulation of immune signaling pathways. The receptor interfaces with the innate immune response pathways and is particularly linked to the Toll-like receptor signaling pathway. It has a relationship with proteins like TLR4 which play important roles in detecting bacterial components and activating myeloid cells. This relationship highlights LILRA5's role in amplifying immune responses against external pathogens.

LILRA5 is associated with inflammatory conditions such as rheumatoid arthritis and inflammatory bowel disease. Its role in promoting inflammation and immune activation directly influences the progression of these diseases. LILRA5 is connected with other immune-related proteins such as IL-1 and TNF-alphan important mediators in inflammatory processes. These connections highlight the relevance of LILRA5 in the pathological inflammatory responses characteristic of these disorders.
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Specifications

Form

Lyophilized

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General info

Function

May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition.

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Product protocols

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Target data

May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition.
See full target information LILRA5
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