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AB202603

Recombinant Human Lingo1 protein (denatured)

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Recombinant Human Lingo1 protein (denatured) is a Human Fragment protein, in the 241 to 337 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

View Alternative Names

LERN1, LRRN6A, UNQ201/PRO227, LINGO1, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A

1 Images
SDS-PAGE - Recombinant Human Lingo1 protein (denatured) (AB202603)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Lingo1 protein (denatured) (AB202603)

15% SDS-PAGE analysis of 3 μg of ab202603.

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q96FE5

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.32% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYL","proteinLength":"Fragment","predictedMolecularWeight":"15.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":337,"aminoAcidStart":241,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96FE5","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed : 14966521, PubMed : 15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed : 15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Post-translational modifications

N-glycosylated. Contains predominantly high-mannose glycans.

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Product protocols

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Target data

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed : 14966521, PubMed : 15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed : 15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
See full target information LINGO1
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Product promise

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