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AB164339

Recombinant Human LMAN2L protein

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Recombinant Human LMAN2L protein is a Human Full Length protein, in the 1 to 348 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

VIPL, PSEC0028, UNQ368/PRO704, LMAN2L, VIP36-like protein, Lectin mannose-binding 2-like, LMAN2-like protein

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SDS-PAGE - Recombinant Human LMAN2L protein (AB164339)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human LMAN2L protein (AB164339)

ab164339 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q9H0V9

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLPEMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":348,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9H0V9","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The LMAN2L protein also known as vesicular integral-membrane protein VIP36-like isoform is approximately 36 kDa in mass. This protein is located mainly in the Golgi apparatus involved in the trafficking of glycoproteins. LMAN2L interacts with N-linked glycoproteins and may function in the secretory pathway. Expression of LMAN2L occurs in various tissues including liver and brain which can suggest its involvement in multiple biological processes.
Biological function summary

LMAN2L plays a part in glycoprotein transport and sorting within the cell. It acts through participation in the transport of glycosylation-modified proteins contributing to their proper localization and function. The protein is part of a larger group involved in cargo selection and shuttling between organelles. This role is important in ensuring functional protein distribution and maintaining cellular homeostasis.

Pathways

LMAN2L's function integrates with the secretory and glycosylation pathways. It affects protein folding and sorting which are essential for maintaining cellular organization and protein maturation. LMAN2L operates alongside proteins such as ERGIC-53 and other lectin family members facilitating proper glycoprotein trafficking from the ER to the Golgi and through the secretory pathway.

Malfunction or misexpression of LMAN2L implicates conditions such as cancer and congenital disorders of glycosylation. LMAN2L in collaboration with calreticulin may contribute to pathologies through disruption in protein trafficking and glycosylation. This protein's dysregulation can influence cell growth and differentiation linking it to tumorigenesis and other developmental anomalies.
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Specifications

Form

Liquid

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General info

Function

May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53.

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Product protocols

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Target data

May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53.
See full target information LMAN2L
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