Recombinant Human Lnx1 protein (GST tag N-Terminus)
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Recombinant Human Lnx1 protein (GST tag N-Terminus) is a Human Fragment protein, in the 19 to 118 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
LNX, PDZRN2, UNQ574/PRO1136, LNX1, E3 ubiquitin-protein ligase LNX, Ligand of Numb-protein X 1, Numb-binding protein 1, PDZ domain-containing RING finger protein 2, RING-type E3 ubiquitin transferase LNX
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Lnx1 protein (GST tag N-Terminus) (AB164648)
ab164648 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
Target data
Product promise
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