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AB164648

Recombinant Human Lnx1 protein (GST tag N-Terminus)

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Recombinant Human Lnx1 protein (GST tag N-Terminus) is a Human Fragment protein, in the 19 to 118 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

LNX, PDZRN2, UNQ574/PRO1136, LNX1, E3 ubiquitin-protein ligase LNX, Ligand of Numb-protein X 1, Numb-binding protein 1, PDZ domain-containing RING finger protein 2, RING-type E3 ubiquitin transferase LNX

1 Images
SDS-PAGE - Recombinant Human Lnx1 protein (GST tag N-Terminus) (AB164648)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Lnx1 protein (GST tag N-Terminus) (AB164648)

ab164648 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q8TBB1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"DNVGNLHFLYSELCKGAFHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERS","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":118,"aminoAcidStart":19,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q8TBB1","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Specifications

Form

Liquid

General info

Function

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.

Product protocols

Target data

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
See full target information LNX1

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