Recombinant Human LOXL1 protein
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Recombinant Human LOXL1 protein is a Human Full Length protein, in the 292 to 574 aa range, expressed in Baculovirus infected Sf9 cells, with >75%, suitable for SDS-PAGE, WB.
View Alternative Names
LOXL, LOXL1, Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human LOXL1 protein (AB172190)
SDS-PAGE analysis of ab172190.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
Additional notes
Affinity purified.
General info
Function
Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers (By similarity). Essential for the elastic fiber homeostasis and for their maintenance at adult age (By similarity).
Sequence similarities
Belongs to the lysyl oxidase family.
Post-translational modifications
The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.. Proteolytic proccessing by a furin-like protease causes removal of N-terminal propeptide resulting in an enzyme largely inactive, but further proteolytic processing by BMP1 results in enzyme activation.
Target data
Product promise
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