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AB93010

Recombinant human LRPAP1 protein

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Recombinant human LRPAP1 protein is a Human Full Length protein, in the 1 to 357 aa range, expressed in Escherichia coli, with >90%, 1.2 EU/mg endotoxin level, suitable for SDS-PAGE, FuncS.

View Alternative Names

A2MRAP, LRPAP1, Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP

Key facts

Purity

>90% SDS-PAGE

Endotoxin level

1.2 EU/mg

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

Active

Accession

P30533

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: Phosphate Buffer, 0.87% Sodium chloride

storage-buffer

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Primary Antibodies

AB76500

Anti-LRPAP1 antibody [EPR3327]

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Proteins & Peptides

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Proteins & Peptides

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Spectrophotometric Data: Epsilon0.1% = 0.926 Intact protein naturally cleaves into ~26 kDa C-terminal portion and ~13 kDa N-terminal fragment. Fragments can be removed by HPLC.Binds with high affinity to certain members of the low-density lipoprotein (LDL) receptor family such as LRP, gp330/megalin, and the very low-density lipoprotein (VLDL) receptor.

Extinction coefficient: 0.93

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Sequence info

[{"sequence":"MAPRRVRSFLRGLPALLLLLLFLGPWPAASHGGKYSREKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRARHNEL","proteinLength":"Full Length","predictedMolecularWeight":"39 kDa","actualMolecularWeight":null,"aminoAcidEnd":357,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P30533","tags":[]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

Additional notes

This endotoxin level in this preparation has been reduced to 22 EU/mg by chromatography.

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General info

Function

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.

Sequence similarities

Belongs to the alpha-2-MRAP family.

Post-translational modifications

N-glycosylated.

Subcellular localisation

Endosome lumen

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Product protocols

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Target data

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
See full target information LRPAP1
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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