Recombinant Human LY6G6D protein (Tagged)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

LY6G6D also known as Lymphocyte Antigen 6 Family Member G6D is a protein that plays a role in immune response. It weighs approximately 13 kDa. This protein is expressed mainly on the surface of immune cells especially granulocytes such as neutrophils. LY6G6D belongs to the Ly6/uPAR family which involves various cell surface proteins with significant roles in immune cell signaling and communication.

Biological function summary

The LY6G6D protein assists in cellular processes related to the immune system. Its role includes the modulation of immune cell activation and response. LY6G6D does not form part of a larger protein complex but interacts with other proteins to fine-tune immune responses. These interactions suggest that LY6G6D participates actively in the immune modulation rather than passive structural roles.

Pathways

LY6G6D integrates within immune signaling cascades and inflammatory pathways. It ties into essential pathways like the NF-kB signaling pathway and the JAK-STAT signaling pathway. These pathways involve proteins such as NF-kB and JAKs which LY6G6D might engage with to influence transcriptional responses and cytokine production enhancing the cell-mediated immune defense.

LY6G6D shows a connection to autoimmune diseases and inflammatory conditions. The protein potentially relates to rheumatoid arthritis where dysfunction in its expression or signaling could exacerbate inflammation. LY6G6D also links to inflammatory bowel disease (IBD) where dysregulation could affect immune cell infiltration and the inflammatory response. This protein may interact with cytokines and chemokines that drive these pathological states indicating its role in disease modulation.