JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB177652

Recombinant Human LZIC protein

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human LZIC protein is a Human Full Length protein, in the 1 to 190 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Protein LZIC, Leucine zipper and CTNNBIP1 domain-containing protein, Leucine zipper and ICAT homologous domain-containing protein, LZIC

1 Images
SDS-PAGE - Recombinant Human LZIC protein (AB177652)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human LZIC protein (AB177652)

15% SDS-PAGE analysis of 3μg ab177652.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Q8WZA0

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.32% Tris HCl

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLSANAGAILSQFEKVSTDLGSGDKILALASFEVEKTKK","proteinLength":"Full Length","predictedMolecularWeight":"23.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":190,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q8WZA0","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The protein LZIC also known as LZ9 or LZC1 functions as a transcriptional regulator involved in cell cycle control and apoptosis. It possesses a mass of approximately 26 kDa and shows expression in various tissues with a notable presence in the brain. Structurally LZIC contains leucine zipper motifs facilitating its role in protein-protein interactions.
Biological function summary

The LZIC protein participates in processes related to cell growth and division as well as programmed cell death. It acts as an integral component of transcriptional regulatory complexes working with other transcription factors to modulate gene expression. By influencing these cellular mechanisms LZIC contributes to maintaining normal cellular function and organismal development.

Pathways

The LZIC protein plays a role in Wnt signaling and apoptosis-related pathways. It interacts closely with key proteins within these pathways including beta-catenin in the Wnt pathway which is important for the regulation of cell fate and proliferation. The interaction with other transcriptional regulators demonstrates its versatility in modulating various cellular processes.

Researchers have associated the LZIC protein with conditions such as cancer and neurological disorders. Dysregulation of LZIC expression may contribute to the development of tumors likely through interactions with oncogenic proteins. Additionally alterations in LZIC function have links to psychiatric disorders with potential interactions involving proteins such as DISC1 in schizophrenia. Scientists view LZIC as a significant target for understanding and potentially treating these diseases.
style
left-column

Specifications

Form

Liquid

Additional notes

ab177652 was purified using conventional chromatography techniques.

style
left-column

General info

Sequence similarities

Belongs to the CTNNBIP1 family.

style
left-column

Product protocols

style
left-column

Target data

See full target information LZIC
style
left-column
style
left-column
style
right-column

Complementary Products

Proteins & Peptides

AB176034

Recombinant Human FLJ36733 protein

SDS-PAGE - Recombinant Human FLJ36733 protein (AB176034)

  • 0
  • 0
Proteins & Peptides

AB176085

Recombinant Human STARD5 protein

SDS-PAGE - Recombinant Human STARD5 protein (AB176085)

  • 0
  • 0
Proteins & Peptides

AB125656

Recombinant human ULK1 protein

Functional Studies - Recombinant human ULK1 protein (AB125656)

  • 0
  • 0
Proteins & Peptides

AB101549

Recombinant human STK38 protein

Functional Studies - Recombinant human STK38 protein (AB101549)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com