Recombinant Human MAGEA8 protein
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Recombinant Human MAGEA8 protein is a Human Full Length protein, in the 1 to 318 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
MAGE8, MAGEA8, Melanoma-associated antigen 8, Cancer/testis antigen 1.8, MAGE-8 antigen, CT1.8
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human MAGEA8 protein (AB202614)
15% SDS-PAGE analysis of ab202614 (3μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MAGEA8 participates in processes that influence cell survival and differentiation. While MAGEA8 does not operate as part of a well-known protein complex it shares functional attributes with other MAGE family members. These proteins can modulate cellular mechanisms often affecting the regulation of apoptosis and growth signals. MAGEA8 may assist in maintaining the delicate balance between cell death and proliferation in specific environments which can be critical during embryogenesis and tumorigenesis.
Pathways
Several factors place MAGEA8 within the context of signaling cascades involved in cell survival and stress response. MAGEA8 interacts with pathways like the p53 signaling pathway known for its role in controlling cell cycle and inducing apoptosis under stress. The interaction with the p53 pathway suggests a possible regulation of cell fate decisions by MAGEA8 much like other MAGE proteins including MAGEA1 and MAGEA3 which are recognized for their roles in similar pathways.
Specifications
Form
Liquid
Additional notes
ab202614 was purified using conventional chromatography.
General info
Function
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Target data
Complementary Products
Product promise
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