Recombinant Human Mannose Phosphate Isomerase protein (denatured)
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Recombinant Human Mannose Phosphate Isomerase protein (denatured) is a Human Full Length protein, in the 1 to 362 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
PMI1, MPI, Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Mannose Phosphate Isomerase protein (denatured) (AB111629)
15% SDS-PAGE showing ab111629 at approximately 41.9kDa (3μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This enzyme facilitates the processing of mannose through the biosynthesis pathways of glycoproteins and glycolipids. Mannose Phosphate Isomerase is not part of a larger protein complex but it functions independently to execute its role within the cell. It ensures that cells have adequate mannose-6-phosphate which is essential for proper glycosylation a process necessary for protein folding and stability.
Pathways
Mannose Phosphate Isomerase influences the hexosamine biosynthesis pathway and glycolysis. In the hexosamine biosynthesis pathway it works closely with enzymes such as phosphomannomutase to provide critical components for the production of glycosaminoglycans and glycoproteins. In glycolysis it helps integrate mannose into energy production processes by providing intermediates necessary for glucose metabolism.
Specifications
Form
Liquid
General info
Function
Isomerase that catalyzes the interconversion of fructose-6-P and mannose-6-P and has a critical role in the supply of D-mannose derivatives required for many eukaryotic glycosylation reactions.
Sequence similarities
Belongs to the mannose-6-phosphate isomerase type 1 family.
Target data
Product promise
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